Browsing Toxins
| T3DB ID | Name CAS Number | Formula Weight | Structure | Type | Mechanism of Toxicity |
|---|---|---|---|---|---|
| T3D1630 | Vanadium(II) oxide 12035-98-2 | OV 66.941 g/mol |  |
| Vanadium damages alveolar macrophages by decreasing the macrophage membrane integrity, thus impairing the cells' phagocytotic ability and viability. The pentavalent fo...more Number of Targets: 47 |
| T3D1624 | Vanadium carbide 12070-10-9 | CH4V 66.984 g/mol |  |
| Vanadium damages alveolar macrophages by decreasing the macrophage membrane integrity, thus impairing the cells' phagocytotic ability and viability. The pentavalent fo...more Number of Targets: 47 |
| T3D0730 | Zinc hydride 14018-82-7 | H2Zn 67.425 g/mol |  |
| Anaemia results from the excessive absorption of zinc suppressing copper and iron absorption, most likely through competitive binding of intestinal mucosal cells. Unba...more Number of Targets: 1 |
| T3D1437 | Chromium(II) oxide 12018-00-7 | CrO 67.996 g/mol |  |
| Trivalent chromium may also form complexes with peptides, proteins, and DNA, resulting in DNA-protein crosslinks, DNA strand breaks, DNA-DNA interstrand crosslinks, ch...more Number of Targets: 5 |
| T3D4203 | Furan 110-00-9 | C4H4O 68.074 g/mol |  |
| Furan is a potent hepatotoxin and hepatocarcinogen in rodents, causing hepatocellular adenomas and carcinomas in rats and mice, and high incidences of cholangiocarcino...more Number of Targets: 3 |
| T3D3566 | Lithium nitrate 7790-69-4 | LiNO3 68.946 g/mol |  |
| Nitrate's toxicity is a result of it's conversion to nitrite once in the body. Nitrite causes the autocatalytic oxidation of oxyhemoglobin to hydrogen peroxide and met...more Number of Targets: 9 |
| T3D3551 | Sodium nitrite 7632-00-0 | NNaO2 68.995 g/mol |  |
| Nitrite causes the autocatalytic oxidation of oxyhemoglobin to hydrogen peroxide and methemoglobin. This elevation of methemoglobin levels is a condition known as meth...more Number of Targets: 9 |
| T3D1696 | Butyronitrile 109-74-0 | C4H7N 69.105 g/mol |  |
| Organic nitriles decompose into cyanide ions both in vivo and in vitro. Consequently the primary mechanism of toxicity for organic nitriles is their production of toxi...more Number of Targets: 39 |
| T3D1690 | Beta-Aminopropionitrile 151-18-8 | C3H6N2 70.093 g/mol |  |
| Organic nitriles decompose into cyanide ions both in vivo and in vitro. Consequently the primary mechanism of toxicity for organic nitriles is their production of toxi...more Number of Targets: 39 |
| T3D3458 | 1-Pentene 109-67-1 | C5H10 70.133 g/mol |  |
| Petroleum distillates are central nervous system depressants and cause pulmonary damage. During metabolism. 1-pentene is oxidized at the double bond and excreted as th...more Number of Targets: 0 |
| T3D3459 | 2-Pentene 109-68-2 | C5H10 70.133 g/mol |  |
| Petroleum distillates are central nervous system depressants and cause pulmonary damage. (A600) Number of Targets: 0 |
| T3D3460 | 2-Methyl-2-butene 513-35-9 | C5H10 70.133 g/mol |  |
| Petroleum distillates are central nervous system depressants and cause pulmonary damage. (A600) Number of Targets: 0 |
| T3D3461 | 3-Methyl-1-butene 563-45-1 | C5H10 70.133 g/mol |  |
| Petroleum distillates are central nervous system depressants and cause pulmonary damage. (A600) Number of Targets: 0 |
| T3D3462 | 2-Methyl-1-butene 563-46-2 | C5H10 70.133 g/mol |  |
| Petroleum distillates are central nervous system depressants and cause pulmonary damage. (A600) Number of Targets: 0 |
| T3D3465 | Cyclopentane 287-92-3 | C5H10 70.133 g/mol |  |
| Petroleum distillates are central nervous system depressants and cause pulmonary damage. (A600) Number of Targets: 0 |
| T3D4972 | Chlorine gas 7782-50-5 | Cl2 70.906 g/mol |  |
| Chlorine is a strong oxidizer that hydrolyzes in water forming hydrochloric and hypochlorous acids. In this form, it can penetrate the cell and form N-chloro-derivativ...more Number of Targets: 0 |
| T3D1139 | Manganese(II) oxide 1344-43-0 | MnO 70.937 g/mol |  |
| Manganese is a cellular toxicant that can impair transport systems, enzyme activities, and receptor functions. It primarily targets the central nervous system, particu...more Number of Targets: 5 |
| T3D0641 | Beryllium carbonate 13106-47-3 | CH2BeO3 71.036 g/mol |  |
| Once in the body, beryllium acts as a hapten and interacts with human leucocyte antigen (HLA) DP presenting cells in the lungs, becoming physically associated with a m...more Number of Targets: 3 |
| T3D1682 | Ethylene cyanohydrin 109-78-4 | C3H5NO 71.078 g/mol |  |
| Cyanide is an inhibitor of cytochrome c oxidase in the fourth complex of the electron transport chain (found in the membrane of the mitochondria of eukaryotic cells). ...more Number of Targets: 39 |
| T3D2573 | Acrylamide 1979-06-01 | C3H5NO 71.078 g/mol |  |
| Acrylamide produces a central-peripheral distal axonopathy when administered chronically. This is characterized functionally by decreases in the monosynaptic reflex an...more Number of Targets: 50 |
| T3D4182 | Malondialdehyde 542-78-9 | C3H4O2 72.063 g/mol |  |
| Uremic toxins such as malondialdehyde are actively transported into the kidneys via organic ion transporters (especially OAT3). Increased levels of uremic toxins can s...more Number of Targets: 5 |
| T3D1536 | Trimethylaluminium 75-24-1 | C3H9Al 72.085 g/mol |  |
| The main target organs of aluminum are the central nervous system and bone. Aluminum binds with dietary phosphorus and impairs gastrointestinal absorption of phosphoru...more Number of Targets: 3 |
| T3D4589 | Butanone 78-93-3 | C4H8O 72.106 g/mol |  |
| Not Available Number of Targets: 1 |
| T3D3428 | Pentane 109-66-0 | C5H12 72.149 g/mol |  |
| Pentane is a central nervous system depressant. It affects the peripheral nervous system through demyelinization and axonal degeneration. (T29) Number of Targets: 0 |
| T3D3429 | Isopentane 78-78-4 | C5H12 72.149 g/mol |  |
| Pentane is a central nervous system depressant. It affects the peripheral nervous system through demyelinization and axonal degeneration. (T29) Number of Targets: 0 |