Browsing Toxins
Displaying toxin 701 - 725 of 3678 in total
| T3DB ID | Name CAS Number | Formula Weight | Structure | Type | Mechanism of Toxicity |
|---|---|---|---|---|---|
| T3D4756 | Triamcinolone 124-94-7 | C21H27FO6 394.434 g/mol |  |
| The antiinflammatory actions of corticosteroids are thought to involve lipocortins, phospholipase A2 inhibitory proteins which, through inhibition of arachidonic acid,...more Number of Targets: 5 |
| T3D1181 | Uranyl nitrate 10102-06-4 | N2O8U 394.038 g/mol |  |
| Uranium is combined with either bicarbonate or a plasma protein in the blood but once in the kidney, it is released and forms complexes with phosphate ligands and prot...more Number of Targets: 10 |
| T3D4573 | Brotizolam 57801-81-7 | C15H10BrClN4S 393.689 g/mol |  |
| Benzodiazepines bind nonspecifically to benzodiazepine receptors BNZ1, which mediates sleep, and BNZ2, which affects affects muscle relaxation, anticonvulsant activity...more Number of Targets: 19 |
| T3D4674 | Amsacrine 51264-14-3 | C21H19N3O3S 393.459 g/mol |  |
| Amsacrine binds to DNA through intercalation and external binding. It has a base specificity for A-T pairs. Rapidly dividing cells are two to four times more sensitive...more Number of Targets: 3 |
| T3D1094 | Barium bromate 13967-90-3 | BaBr2O6 393.131 g/mol |  |
| Barium is a competitive potassium channel antagonist that blocks the passive efflux of intracellular potassium, resulting in a shift of potassium from extracellular to...more Number of Targets: 27 |
| T3D4961 | Deoxycholic acid 83-44-3 | C24H40O4 392.572 g/mol |  |
| Not Available Number of Targets: 3 |
| T3D4982 | Dexamethasone 50-02-2 | C22H29FO5 392.461 g/mol |  |
| Dexamethasone is a glucocorticoid agonist. Unbound dexamethasone crosses cell membranes and binds with high affinity to specific cytoplasmic glucocorticoid receptors. ...more Number of Targets: 7 |
| T3D1850 | Permethrin 52645-53-1 | C21H20Cl2O3 391.288 g/mol |  |
| Pyrethroids exert their effect by prolonging the open phase of the sodium channel gates when a nerve cell is excited. They appear to bind to the membrane lipid phase i...more Number of Targets: 26 |
| T3D1112 | Barium iodide 13718-50-8 | BaI2 391.136 g/mol |  |
| Barium is a competitive potassium channel antagonist that blocks the passive efflux of intracellular potassium, resulting in a shift of potassium from extracellular to...more Number of Targets: 21 |
| T3D2874 | Meclizine 569-65-3 | C25H27ClN2 390.948 g/mol |  |
| Along with its actions as an antagonist at H1-receptors, meclizine also possesses anticholinergic, central nervous system depressant, and local anesthetic effects. Mec...more Number of Targets: 2 |
| T3D1994 | 3,4',5-Tribromobiphenyl 72416-87-6 | C12H7Br3 390.896 g/mol |  |
| The exact mechanism of toxicty of PBBs varies depending on the specific congener. The predominant interaction is believed to involve the aryl hydrocarbon receptor (AhR...more Number of Targets: 1 |
| T3D1982 | 3,4,4'-Tribromobiphenyl 6683-35-8 | C12H7Br3 390.896 g/mol |  |
| The exact mechanism of toxicty of PBBs varies depending on the specific congener. The predominant interaction is believed to involve the aryl hydrocarbon receptor (AhR...more Number of Targets: 1 |
| T3D1980 | 2,4,4'-Tribromobiphenyl 6430-90-6 | C12H7Br3 390.896 g/mol |  |
| The exact mechanism of toxicty of PBBs varies depending on the specific congener. The predominant interaction is believed to involve the aryl hydrocarbon receptor (AhR...more Number of Targets: 1 |
| T3D1979 | 2,4',6-Tribromobiphenyl 64258-03-3 | C12H7Br3 390.896 g/mol |  |
| The exact mechanism of toxicty of PBBs varies depending on the specific congener. The predominant interaction is believed to involve the aryl hydrocarbon receptor (AhR...more Number of Targets: 1 |
| T3D1966 | 2,4',5-Tribromobiphenyl 59080-36-3 | C12H7Br3 390.896 g/mol |  |
| The exact mechanism of toxicty of PBBs varies depending on the specific congener. The predominant interaction is believed to involve the aryl hydrocarbon receptor (AhR...more Number of Targets: 1 |
| T3D1965 | 2,3',5-Tribromobiphenyl 59080-35-2 | C12H7Br3 390.896 g/mol |  |
| The exact mechanism of toxicty of PBBs varies depending on the specific congener. The predominant interaction is believed to involve the aryl hydrocarbon receptor (AhR...more Number of Targets: 1 |
| T3D1964 | 2,2',5-Tribromobiphenyl 59080-34-1 | C12H7Br3 390.896 g/mol |  |
| The exact mechanism of toxicty of PBBs varies depending on the specific congener. The predominant interaction is believed to involve the aryl hydrocarbon receptor (AhR...more Number of Targets: 1 |
| T3D1963 | 2,4,6-Tribromobiphenyl 59080-33-0 | C12H7Br3 390.896 g/mol |  |
| The exact mechanism of toxicty of PBBs varies depending on the specific congener. The predominant interaction is believed to involve the aryl hydrocarbon receptor (AhR...more Number of Targets: 1 |
| T3D1956 | Tribromobiphenyl 51202-79-0 | C12H7Br3 390.896 g/mol |  |
| The exact mechanism of toxicty of PBBs varies depending on the specific congener. The predominant interaction is believed to involve the aryl hydrocarbon receptor (AhR...more Number of Targets: 1 |
| T3D1920 | 3,4,5-Tribromobiphenyl 115245-08-4 | C12H7Br3 390.896 g/mol |  |
| The exact mechanism of toxicty of PBBs varies depending on the specific congener. The predominant interaction is believed to involve the aryl hydrocarbon receptor (AhR...more Number of Targets: 1 |
| T3D1919 | 2,4,5-Tribromobiphenyl 115245-07-3 | C12H7Br3 390.896 g/mol |  |
| The exact mechanism of toxicty of PBBs varies depending on the specific congener. The predominant interaction is believed to involve the aryl hydrocarbon receptor (AhR...more Number of Targets: 1 |
| T3D2115 | 1,2,3,4,6,8-Hexachlorodibenzo-p-dioxin 58200-67-2 | C12H2Cl6O2 390.861 g/mol |  |
| CDDs cause their toxic effects by binding to the aryl hydrocarbon receptor and subsequently altering the transcription of certain genes. The affinity for the Ah recept...more Number of Targets: 3 |
| T3D2114 | 1,2,4,6,8,9-Hexachlorodibenzo-p-dioxin 58802-09-8 | C12H2Cl6O2 390.861 g/mol |  |
| CDDs cause their toxic effects by binding to the aryl hydrocarbon receptor and subsequently altering the trascription of certain genes. The affinity for the Ah recepto...more Number of Targets: 4 |
| T3D2113 | 1,2,3,4,6,9-Hexachlorodibenzo-p-dioxin 58200-68-3 | C12H2Cl6O2 390.861 g/mol |  |
| CDDs cause their toxic effects by binding to the aryl hydrocarbon receptor and subsequently altering the transcription of certain genes. The affinity for the Ah recept...more Number of Targets: 3 |
| T3D2112 | 1,2,3,6,8,9-Hexachlorodibenzo-p-dioxin 58200-69-4 | C12H2Cl6O2 390.861 g/mol |  |
| CDDs cause their toxic effects by binding to the aryl hydrocarbon receptor and subsequently altering the transcription of certain genes. The affinity for the Ah recept...more Number of Targets: 3 |