Browsing Toxins
Displaying toxin 3551 - 3575 of 3678 in total
| T3DB ID | Name CAS Number | Formula Weight | Structure | Type | Mechanism of Toxicity |
|---|---|---|---|---|---|
| T3D2523 | Scyllatoxin 142948-19-4 | Not Available 3430.130 g/mol |  |
| Scyllatoxin blocks small conductance calcium-activated potassium channels. This inhibits the slow after-hyperpolarisation that follows an action potential in some nerv...more Number of Targets: 3 |
| T3D2525 | Tamapin 508220-81-3 | Not Available 3465.100 g/mol |  |
| Tamapin is a selective, potent, and reversible blocker of small conductance calcium-dependent potassium channels. It inhibits SK2 with the highest affinity, SK3 with a...more Number of Targets: 3 |
| T3D2526 | Tityustoxin (Tityus serrulatus ) 39465-37-7 | Not Available 6997.935 g/mol |  |
| Tityustoxin binds to voltage-dependent sodium and potassium channels. alpha-Type tityustoxin inhibits the inactivation of the activated sodium channels by binding to s...more Number of Targets: 14 |
| T3D2539 | Calciseptine 134710-25-1 | Not Available 7044.155 g/mol |  |
| Calciseptine is a specific blocker of the L-type calcium channel, and as a result also a smooth muscle relaxant and an inhibitor of cardiac contractions. (T170) Number of Targets: 8 |
| T3D2540 | Calcicludine 178037-96-2 | Not Available 6986.205 g/mol |  |
| Calcicludine inhibits high-voltage-activated calcium channels, especially of the L-type. (L1092) Number of Targets: 10 |
| T3D2541 | Cardiotoxin (Naja atra) 155808-00-7 | Not Available 8991.970 g/mol |  |
| Cardiotoxin binds to the cell membrane and depolarizes cardiomyocytes. It also shows lytic activities on many other cells, including red blood cells. It also targets t...more Number of Targets: 11 |
| T3D2542 | Crotamine 58740-15-1 | Not Available 7518.980 g/mol |  |
| Crotamine specifically modifies voltage-sensitive sodium channels, it exhibits analgesic activity and causes severe muscle necrosis by a non-enzymatic mechanism. It al...more Number of Targets: 14 |
| T3D2543 | Crotoxin 9007-40-3 | Not Available 15272.965 g/mol |  |
| Crotoxin inhibits neuromuscular transmission by presynaptically blocking acetylcholine release from the nerve termini. (T170) Number of Targets: 0 |
| T3D2544 | Convulxin 37206-04-5 | Not Available 18140.725 g/mol |  |
| Convulxin binds to the platelet and collagen receptor, glycoprotein VI (GPVI). This causes platelet activation in the blood forming clots and a build up of pressure, w...more Number of Targets: 1 |
| T3D0793 | Tremolite Asbestos 77536-68-6 | (Na, K)0-1Ca2Mg5Si8O22(OH)2 Not Available |  |
| When asbestos fibers are inhaled, many are deposited on the epithelial surface of the respiratory tree. Fibers that are retained in the lung or mesothelium for long pe...more Number of Targets: 1 |
| T3D2545 | Dendrotoxin (Dendroaspis polylepis polylepis) 119128-61-9 | Not Available 7155.305 g/mol |  |
| Dendrotoxins block particular subtypes of voltage-gated potassium channels in neurons, thereby prolonging the duration of action potentials and enhancing the release o...more Number of Targets: 23 |
| T3D0794 | Actinolite Asbestos 77536-66-4 | (Na, K)0-1Ca2(Mg, Fe)5Si8O22(OH)2 Not Available |  |
| When asbestos fibers are inhaled, many are deposited on the epithelial surface of the respiratory tree. Fibers that are retained in the lung or mesothelium for long pe...more Number of Targets: 1 |
| T3D2546 | Dendrotoxin (Dendroaspis angusticeps) 74504-53-3 | Not Available 3417.825 g/mol |  |
| Dendrotoxins block particular subtypes of voltage-gated potassium channels in neurons, thereby prolonging the duration of action potentials and enhancing the release o...more Number of Targets: 23 |
| T3D0795 | Anthophyllite Asbestos 77536-67-5 | (Na, K)0-1Mg2(Mg, Fe)5Si8O22(OH)2, Mg/(Mg + Fe) > 0.6 Not Available |  |
| When asbestos fibers are inhaled, many are deposited on the epithelial surface of the respiratory tree. Fibers that are retained in the lung or mesothelium for long pe...more Number of Targets: 1 |
| T3D2547 | Taicatoxin 112154-17-3 | Not Available 9711.255 g/mol |  |
| Taicatoxin blocks the voltage-dependent L-type calcium channels from the heart and on the small conductance calcium-activated potassium channels in the brain. (L1105) Number of Targets: 11 |
| T3D2549 | Eledoisin (Eledone cirrhosa) 69-25-0 | Not Available 1206.410 g/mol |  |
| Eledoisin is a tachykinin peptide. Tachykinins excite neurons, evoke behavioural responses, are potent vasodilators and secretagogues, and contract (directly or indire...more Number of Targets: 3 |
| T3D2552 | Sticholysin 269658-04-0; 183449-91-4 | Not Available 19390.885 g/mol |  |
| Sticholysin is a cardiac stimulatory and hemolytic pore-forming protein. Pore formation likely proceeds by membrane binding via a surface rich in aromatic residues, fo...more Number of Targets: 0 |
| T3D1567 | Diaspore 14457-84-2 | AlO(OH) 59.988 g/mol |  |
| The main target organs of aluminum are the central nervous system and bone. Aluminum binds with dietary phosphorus and impairs gastrointestinal absorption of phosphoru...more Number of Targets: 3 |
| T3D3070 | Abrin-a 53597-23-2 | Not Available 59243.125 g/mol |  |
| Abrin works by penetrating the cells of the body and inhibiting cell protein synthesis. By attaching to a carbohydrate chain on the cell surface, the abrin molecule an...more Number of Targets: 1 |
| T3D3071 | Abrin-b Not Available | Not Available 59114.060 g/mol |  |
| Abrin works by penetrating the cells of the body and inhibiting cell protein synthesis. By attaching to a carbohydrate chain on the cell surface, the abrin molecule an...more Number of Targets: 1 |
| T3D3072 | Abrin-c 53597-24-3 | Not Available 62817.245 g/mol |  |
| Abrin works by penetrating the cells of the body and inhibiting cell protein synthesis. By attaching to a carbohydrate chain on the cell surface, the abrin molecule an...more Number of Targets: 1 |
| T3D3073 | Abrin-d 1393-62-0 | Not Available 58869.605 g/mol |  |
| Abrin works by penetrating the cells of the body and inhibiting cell protein synthesis. By attaching to a carbohydrate chain on the cell surface, the abrin molecule an...more Number of Targets: 1 |
| T3D3583 | Botulinum toxin 93384-43-1 | Not Available 149452.615 g/mol |  |
| Botulinum toxin is a two-chain polypeptide with a 100-kDa heavy chain joined by a disulfide bond to a 50-kDa light chain. Following the attachment of the toxin heavy c...more Number of Targets: 2 |
| T3D3584 | Botulinum neurotoxin type G Not Available | Not Available 149033.235 g/mol |  |
| Botulinum toxin is a two-chain polypeptide with a 100-kDa heavy chain joined by a disulfide bond to a 50-kDa light chain. Following the attachment of the toxin heavy c...more Number of Targets: 0 |
| T3D3088 | Thionin (Pyrularia pubera) Not Available | Not Available 5288.110 g/mol |  |
| Thionins are thought to attack the cell membrane and render it permeable. This results in the inhibition of sugar uptake and allows potassium and phosphate ions, prote...more Number of Targets: 0 |