Browsing Toxins
Displaying toxin 326 - 350 of 3678 in total
| T3DB ID | Name CAS Number | Formula Weight | Structure | Type | Mechanism of Toxicity |
|---|---|---|---|---|---|
| T3D1747 | Platinum(IV) bromide 68936-92-1 | Br4Pt 514.700 g/mol |  |
| Bromine is a powerful oxidizing agent and is able to release oxygen free radicals from the water in mucous membranes. These free radicals are also potent oxidizers and...more Number of Targets: 6 |
| T3D3711 | Roridin E 16891-85-3 | C29H38O8 514.607 g/mol |  |
| Unlike many other mycotoxins, trichothecenes do not require metabolic activation to exert their biological activity, instead directly reacting with cellular components...more Number of Targets: 2 |
| T3D3999 | Perfluorodecanoic acid 335-76-2 | C10HF19O2 514.083 g/mol |  |
| Not Available Number of Targets: 5 |
| T3D3747 | Territrem C 89020-33-7 | C28H32O9 512.548 g/mol |  |
| Territrem C is a cholinesterase or acetylcholinesterase (AChE) inhibitor. A cholinesterase inhibitor (or 'anticholinesterase') suppresses the action of acetylcholinest...more Number of Targets: 1 |
| T3D3782 | Verruculogen 12771-72-1 | C27H33N3O7 511.567 g/mol |  |
| Tremorgenic mycotoxins exert their toxic effects by interfering with neurotransmitter release, possibly by causing degeneration of nerve terminals. They are thought to...more Number of Targets: 28 |
| T3D0356 | Mercury(II) thiocyanate 592-85-8 | C4HgK2N4S4 511.120 g/mol |  |
| High-affinity binding of the divalent mercuric ion to thiol or sulfhydryl groups of proteins is believed to be the major mechanism for the activity of mercury. Through...more Number of Targets: 88 |
| T3D4840 | Propylene glycol mono- and diesters of fats and fatty acids 107-98-2 | C32H62O4 510.832 g/mol |  |
| Not Available Number of Targets: 2 |
| T3D3746 | Territrem A 70407-19-1 | C28H30O9 510.532 g/mol |  |
| Territrem A is a cholinesterase or acetylcholinesterase (AChE) inhibitor. A cholinesterase inhibitor (or 'anticholinesterase') suppresses the action of acetylcholinest...more Number of Targets: 1 |
| T3D1848 | Flumethrin 69770-45-2 | C28H22Cl2FNO3 510.384 g/mol |  |
| Pyrethroids exert their effect by prolonging the open phase of the sodium channel gates when a nerve cell is excited. They appear to bind to the membrane lipid phase i...more Number of Targets: 19 |
| T3D1885 | Tetraphenylantimony bromide 16894-69-2 | C24H20BrSb 510.080 g/mol |  |
| The inhalation data suggests that the myocardium is a target of antimony toxicity. It is possible that antimony affects circulating glucose by interfering with enzymes...more Number of Targets: 20 |
| T3D4932 | Dimethyl dialkyl ammonium chloride 8001-54-5 | C35H74N 508.968 g/mol |  |
| Not Available Number of Targets: 5 |
| T3D1362 | Mersalyl acid 486-67-9 | C12H14HgNNaO7 507.820 g/mol |  |
| High-affinity binding of the divalent mercuric ion to thiol or sulfhydryl groups of proteins is believed to be the major mechanism for the activity of mercury. Through...more Number of Targets: 50 |
| T3D4051 | Gymnodimine 173792-58-0 | C32H45NO4 507.704 g/mol |  |
| Gymnodimine exerts its toxic effects via binding to nicotinic acetylcholine receptors with picomolar affinities with no sign of apparent reversibility in short time fr...more Number of Targets: 0 |
| T3D3678 | Cytochalasin D 22144-77-0 | C30H37NO6 507.618 g/mol |  |
| Cytochalasins are known to bind to the barbed, fast growing plus ends of microfilaments, which then blocks both the assembly and disassembly of individual actin monome...more Number of Targets: 6 |
| T3D3677 | Cytochalasin C 22144-76-9 | C30H37NO6 507.618 g/mol |  |
| Cytochalasins are known to bind to the barbed, fast growing plus ends of microfilaments, which then blocks both the assembly and disassembly of individual actin monome...more Number of Targets: 6 |
| T3D4276 | Adenosine triphosphate 56-65-5 | C10H16N5O13P3 507.181 g/mol |  |
| ATP is able to store and transport chemical energy within cells. ATP also plays an important role in the synthesis of nucleic acids. ATP can be produced by various cel...more Number of Targets: 42 |
| T3D2863 | Amprenavir 161814-49-9 | C25H35N3O6S 505.627 g/mol |  |
| Amprenavir inhibits the HIV viral proteinase enzyme which prevents cleavage of the gag-pol polyprotein, resulting in noninfectious, immature viral particles. Number of Targets: 5 |
| T3D1035 | Deltamethrin 52918-63-5 | C22H19Br2NO3 505.199 g/mol |  |
| Both type I and type II pyrethroids exert their effect by prolonging the open phase of the sodium channel gates when a nerve cell is excited. They appear to bind to th...more Number of Targets: 26 |
| T3D0932 | Biscarbofuran N,N'-disulfide 39995-74-9 | C24H28N2O6S2 504.619 g/mol |  |
| Biscarbofuran N,N'-disulfide is a cholinesterase or acetylcholinesterase (AChE) inhibitor. Carbamates form unstable complexes with chlolinesterases by carbamoylation o...more Number of Targets: 2 |
| T3D3875 | Mesosulfuron-methyl 208465-21-8 | C17H21N5O9S2 503.507 g/mol |  |
| Not Available Number of Targets: 1 |
| T3D1898 | Tris(1-naphthyl)antimony 27309-70-2 | C30H21Sb 503.250 g/mol |  |
| The inhalation data suggests that the myocardium is a target of antimony toxicity. It is possible that antimony affects circulating glucose by interfering with enzymes...more Number of Targets: 20 |
| T3D1849 | Tau-fluvalinate 102851-06-9 | C26H22ClF3N2O3 502.913 g/mol |  |
| Pyrethroids exert their effect by prolonging the open phase of the sodium channel gates when a nerve cell is excited. They appear to bind to the membrane lipid phase i...more Number of Targets: 20 |
| T3D1039 | Fluvalinate 69409-94-5 | C26H22ClF3N2O3 502.913 g/mol |  |
| Both type I and type II pyrethroids exert their effect by prolonging the open phase of the sodium channel gates when a nerve cell is excited. They appear to bind to th...more Number of Targets: 19 |
| T3D3720 | Verrucarin A 3148-09-2 | C27H34O9 502.554 g/mol |  |
| Unlike many other mycotoxins, trichothecenes do not require metabolic activation to exert their biological activity, instead directly reacting with cellular components...more Number of Targets: 2 |
| T3D1321 | Phenarsazine oxide 58-36-6 | C24H16As2O3 502.225 g/mol |  |
| Arsenic and its metabolites disrupt ATP production through several mechanisms. At the level of the citric acid cycle, arsenic inhibits pyruvate dehydrogenase and by co...more Number of Targets: 44 |