Browsing Toxins
Displaying toxin 3026 - 3050 of 3678 in total
| T3DB ID | Name CAS Number | Formula Weight | Structure | Type | Mechanism of Toxicity |
|---|---|---|---|---|---|
| T3D4161 | Homocysteine 454-29-5 | C4H9NO2S 135.185 g/mol |  |
| Nitrosylation converts homocysteine (Hcy) into a methionine analogue, S-nitroso-Homocysteine, which can substitute for methionine in protein synthesis in biological sy...more Number of Targets: 5 |
| T3D4279 | Adenine 73-24-5 | C5H5N5 135.127 g/mol |  |
| Adenine forms adenosine, a nucleoside, when attached to ribose, and deoxyadenosine when attached to deoxyribose, and it forms adenosine triphosphate (ATP), a nucleotid...more Number of Targets: 10 |
| T3D1271 | Tin(II) oxide 21651-19-4 | OSn 134.710 g/mol |  |
| Inorganic and organic tin compounds are weak inhibitors of alcohol dehydrogenase. (A183) Number of Targets: 7 |
| T3D1209 | Copper(II) chloride 7447-39-4 | Cl2Cu 134.452 g/mol |  |
| Excess copper is sequestered within hepatocyte lysosomes, where it is complexed with metallothionein. Copper hepatotoxicity is believed to occur when the lysosomes bec...more Number of Targets: 7 |
| T3D4882 | p-Cymene 99-87-6 | C10H14 134.218 g/mol |  |
| Not Available Number of Targets: 1 |
| T3D4761 | Butylbenzene 104-51-8 | C10H14 134.218 g/mol |  |
| Not Available Number of Targets: 1 |
| T3D4917 | Polypropylene glycol (m w 1,200-3,000) 25322-69-4 | C6H14O3 134.174 g/mol |  |
| Not Available Number of Targets: 1 |
| T3D0765 | Silver cyanide 506-64-9 | CAgN 133.886 g/mol |  |
| Cyanide is an inhibitor of cytochrome c oxidase in the fourth complex of the electron transport chain (found in the membrane of the mitochondria of eukaryotic cells). ...more Number of Targets: 51 |
| T3D0097 | 1,1,1-Trichloroethane 71-55-6 | C2H3Cl3 133.404 g/mol |  |
| 1,1,1-Trichloroethane is a cholinesterase or acetylcholinesterase (AChE) inhibitor. A cholinesterase inhibitor (or 'anticholinesterase') suppresses the action of acety...more Number of Targets: 41 |
| T3D0163 | 1,1,2-Trichloroethane 79-00-5 | C2H3Cl3 133.404 g/mol |  |
| Acyl chlorides and free radicals formed during the metabolism of 1,1,2-trichloroethane are reactive metabolites that can bind to proteins and nucleic acids (DNA, RNA),...more Number of Targets: 5 |
| T3D1493 | Aluminium chloride 7446-70-0 | AlCl3 133.341 g/mol |  |
| The main target organs of aluminum are the central nervous system and bone. Aluminum binds with dietary phosphorus and impairs gastrointestinal absorption of phosphoru...more Number of Targets: 4 |
| T3D2881 | Tranylcypromine 155-09-9 | C9H11N 133.190 g/mol |  |
| Tranylcypromine irreversibly and nonselectively inhibits monoamine oxidase (MAO). Within neurons, MAO appears to regulate the levels of monoamines released upon synapt...more Number of Targets: 4 |
| T3D1686 | Mandelonitrile 532-28-5 | C8H7NO 133.147 g/mol |  |
| Organic nitriles decompose into cyanide ions both in vivo and in vitro. Consequently the primary mechanism of toxicity for organic nitriles is their production of toxi...more Number of Targets: 39 |
| T3D0651 | Beryllium nitrate 13597-99-4 | BeN2O6 133.022 g/mol |  |
| Once in the body, beryllium acts as a hapten and interacts with human leucocyte antigen (HLA) DP presenting cells in the lungs, becoming physically associated with a m...more Number of Targets: 12 |
| T3D3974 | Cesium 7440-46-2 | Cs 132.906 g/mol |  |
| Not Available Number of Targets: 1 |
| T3D1600 | Silver acetylide 7659-31-6 | C2HAg 132.898 g/mol |  |
| Metallic silver is oxidized and may deposit in the tissues, causing arygria. The silver ion is known to inhibit glutathione peroxidase and NA+,K+-ATPase activity, disr...more Number of Targets: 17 |
| T3D4985 | Cinnamaldehyde 104-55-2 | C9H8O 132.159 g/mol |  |
| Cinnamaldehyde is an allergen. The physiologic effect of cinnamaldehyde is by means of increased histamine release and cell-mediated immunity. Number of Targets: 2 |
| T3D4362 | L-Asparagine 70-47-3 | C4H8N2O3 132.118 g/mol |  |
| Asparagine, a non-essential amino acid is important in the metabolism of toxic ammonia in the body through the action of asparagine synthase which attaches ammonia to ...more Number of Targets: 6 |
| T3D4359 | Glutaric acid 110-94-1 | C5H8O4 132.115 g/mol |  |
| Accumulation of glutaric acid in the body has been shown to be toxic. The accumulation of glutaric acid ranging from slightly or intermittently elevated urinary glutar...more Number of Targets: 1 |
| T3D4461 | Ethylmalonic acid 601-75-2 | C5H8O4 132.115 g/mol |  |
| Ethylmalonic acid is identified in the urine of patients with short-chain acyl-coenzyme A dehydrogenase deficiency, which is a fatty acid metabolism disorder. Number of Targets: 1 |
| T3D1299 | Arsenic trifluoride 7784-35-2 | AsF3 131.917 g/mol |  |
| Arsenic and its metabolites disrupt ATP production through several mechanisms. At the level of the citric acid cycle, arsenic inhibits pyruvate dehydrogenase and by co...more Number of Targets: 44 |
| T3D0016 | Trichloroethylene 1979-01-06 | C2HCl3 131.388 g/mol |  |
| The toxic and carcinogenic effects of trichloroethylene are believed to be caused mainly by its metabolites, including trichloroacetic acid, dichloroacetic acid, and c...more Number of Targets: 50 |
| T3D4364 | L-Isoleucine 73-32-5 | C6H13NO2 131.173 g/mol |  |
| (Applies to Valine, Leucine and Isoleucine) This group of essential amino acids are identified as the branched-chain amino acids, BCAAs. Because this arrangement of ca...more Number of Targets: 6 |
| T3D4365 | L-Leucine 61-90-5 | C6H13NO2 131.173 g/mol |  |
| This group of essential amino acids are identified as the branched-chain amino acids, BCAAs. Because this arrangement of carbon atoms cannot be made by humans, these a...more Number of Targets: 10 |
| T3D4290 | Creatine 57-00-1 | C4H9N3O2 131.133 g/mol |  |
| In the muscles, a fraction of the total creatine binds to phosphate - forming creatine phosphate. The reaction is catalysed by creatine kinase, and the result is phosp...more Number of Targets: 7 |