Browsing Toxins
Displaying toxin 2826 - 2850 of 3678 in total
| T3DB ID | Name CAS Number | Formula Weight | Structure | Type | Mechanism of Toxicity |
|---|---|---|---|---|---|
| T3D0142 | Bromine 7726-95-6 | Br2 159.808 g/mol |  |
| Bromine is a powerful oxidizing agent and is able to release oxygen free radicals from the water in mucous membranes. These free radicals are also potent oxidizers and...more Number of Targets: 7 |
| T3D1215 | Copper(II) sulfate 7758-98-7 | CuO4S 159.609 g/mol |  |
| Excess copper is sequestered within hepatocyte lysosomes, where it is complexed with metallothionein. Copper hepatotoxicity is believed to occur when the lysosomes bec...more Number of Targets: 6 |
| T3D1197 | Copper(I) sulfide 22205-45-4 | Cu2S 159.157 g/mol |  |
| Excess copper is sequestered within hepatocyte lysosomes, where it is complexed with metallothionein. Copper hepatotoxicity is believed to occur when the lysosomes bec...more Number of Targets: 6 |
| T3D1648 | Palladium(II) cyanide 2035-66-7 | C2N2Pd 158.450 g/mol |  |
| Cyanide is an inhibitor of cytochrome c oxidase in the fourth complex of the electron transport chain (found in the membrane of the mitochondria of eukaryotic cells). ...more Number of Targets: 48 |
| T3D1439 | Chromium(III) chloride 10025-73-7 | Cl3Cr 158.355 g/mol |  |
| Trivalent chromium may also form complexes with peptides, proteins, and DNA, resulting in DNA-protein crosslinks, DNA strand breaks, DNA-DNA interstrand crosslinks, ch...more Number of Targets: 5 |
| T3D4931 | 3,7-Dimethyl-3-octanol 78-69-3 | C10H22O 158.281 g/mol |  |
| Not Available Number of Targets: 1 |
| T3D4839 | Isoamyl butyrate 106-27-4 | C9H18O2 158.238 g/mol |  |
| Not Available Number of Targets: 2 |
| T3D4636 | 1,2-Naphthoquinone 524-42-5 | C10H6O2 158.153 g/mol |  |
| 1,2-Naphthoquinone is a cholinesterase or acetylcholinesterase (AChE) inhibitor. A cholinesterase inhibitor (or 'anticholinesterase') suppresses the action of acetylch...more Number of Targets: 10 |
| T3D4637 | 1,4-Naphthoquinone 130-15-4 | C10H6O2 158.153 g/mol |  |
| Not Available Number of Targets: 5 |
| T3D4471 | Succinylacetone 51568-18-4 | C7H10O4 158.152 g/mol |  |
| Not Available Number of Targets: 1 |
| T3D4936 | Allantoin 97-59-6 | C4H6N4O3 158.115 g/mol |  |
| Not Available Number of Targets: 2 |
| T3D2455 | Ibotenic acid 2552-55-8 | C5H6N2O4 158.112 g/mol |  |
| A portion of ibotenic acid is metabolized to muscimol, a potent GABAA agonist, activating the receptor for the brain's major inhibitory neurotransmitter, GABA. Muscimo...more Number of Targets: 12 |
| T3D1136 | Potassium permanganate 7722-64-7 | KMnO4 158.034 g/mol |  |
| Manganese is a cellular toxicant that can impair transport systems, enzyme activities, and receptor functions. It primarily targets the central nervous system, particu...more Number of Targets: 5 |
| T3D1151 | Manganese(III) oxide 1317-34-6 | Mn2O3 157.874 g/mol |  |
| Manganese is a cellular toxicant that can impair transport systems, enzyme activities, and receptor functions. It primarily targets the central nervous system, particu...more Number of Targets: 5 |
| T3D1631 | Vanadium(III) chloride 7718-98-1 | Cl3V 157.301 g/mol |  |
| Vanadium damages alveolar macrophages by decreasing the macrophage membrane integrity, thus impairing the cells' phagocytotic ability and viability. The pentavalent fo...more Number of Targets: 47 |
| T3D2839 | Paramethadione 115-67-3 | C7H11NO3 157.167 g/mol |  |
| Dione anticonvulsants such as paramethadione reduce T-type calcium currents in thalamic neurons (including thalamic relay neurons). This inhibits corticothalamic trans...more Number of Targets: 1 |
| T3D1817 | Benzeneselenol 645-96-5 | C6H6Se 157.070 g/mol |  |
| Selenium readily substitutes for sulfur in biomolecules and in many biochemical reactions, especially when the concentration of selenium is high and the concentration ...more Number of Targets: 0 |
| T3D1779 | Bromobenzene 108-86-1 | C6H5Br 157.008 g/mol |  |
| The hepatotoxicity of bromobenzene is due to the production of reactive metabolites that modify or alkylated DNA, RNA and proteins. These reactive metabolites arise f...more Number of Targets: 11 |
| T3D1496 | Aluminium dodecaboride 12041-54-2 | AlB12 156.714 g/mol |  |
| The main target organs of aluminum are the central nervous system and bone. Aluminum binds with dietary phosphorus and impairs gastrointestinal absorption of phosphoru...more Number of Targets: 3 |
| T3D1237 | Tin(II) fluoride 7783-47-3 | F2Sn 156.710 g/mol |  |
| Inorganic and organic tin compounds are weak inhibitors of alcohol dehydrogenase. (A183) Number of Targets: 7 |
| T3D4183 | Decanal 112-31-2 | C10H20O 156.265 g/mol |  |
| Uremic toxins such as decanal are actively transported into the kidneys via organic ion transporters (especially OAT3). Increased levels of uremic toxins can stimulate...more Number of Targets: 3 |
| T3D3224 | Menthol 2216-51-5 | C10H20O 156.265 g/mol |  |
| Menthol acts as a weak Kappa Opioid Receptor Agonist. Number of Targets: 4 |
| T3D4180 | 4-Hydroxynonenal 75899-68-2 | C9H16O2 156.222 g/mol |  |
| Uremic toxins such as 4-Hydroxynonenal are actively transported into the kidneys via organic ion transporters (especially OAT3). Increased levels of uremic toxins can ...more Number of Targets: 16 |
| T3D1048 | 2-Nitromethylene-azepane 61018-99-3 | C7H12N2O2 156.182 g/mol |  |
| Acts as a neurotransmitter mimic , having both excitatory and depressant effects, eventually blocking postsynaptic nicotinic receptors. (T10) Number of Targets: 5 |
| T3D1058 | (2Z)-1-Ethyl-2-(nitromethylidene)pyrrolidine 26171-04-0 | C7H12N2O2 156.182 g/mol |  |
| Acts as a neurotransmitter mimic , having both excitatory and depressant effects, eventually blocking postsynaptic nicotinic receptors. (T10) Number of Targets: 5 |