Browsing Toxins
Displaying toxin 2801 - 2825 of 3678 in total
| T3DB ID | Name CAS Number | Formula Weight | Structure | Type | Mechanism of Toxicity |
|---|---|---|---|---|---|
| T3D4870 | Trichloroacetic acid 76-03-9 | C2HCl3O2 163.387 g/mol |  |
| Not Available Number of Targets: 1 |
| T3D1637 | Vanadyl sulfate 27774-13-6 | O5SV 163.004 g/mol |  |
| Vanadium damages alveolar macrophages by decreasing the macrophage membrane integrity, thus impairing the cells' phagocytotic ability and viability. The pentavalent fo...more Number of Targets: 47 |
| T3D3947 | 3,4-Dichlorophenol 95-77-2 | C6H4Cl2O 163.001 g/mol |  |
| Not Available Number of Targets: 4 |
| T3D0209 | 2,4-Dichlorophenol 120-83-2 | C6H4Cl2O 163.001 g/mol |  |
| Chlorophenols have moderately high lipophilicity. Absorption through the gastrointestinal tract is by simple diffusion and is expected to be both rapid and virtually c...more Number of Targets: 3 |
| T3D3822 | Dazomet 533-74-4 | C5H10N2S2 162.276 g/mol |  |
| Not Available Number of Targets: 13 |
| T3D0799 | Nicotine 54-11-5 | C10H14N2 162.232 g/mol |  |
| Nicotine is a stimulant drug that acts as an agonist at nicotinic acetylcholine receptors. These are ionotropic receptors composed up of five homomeric or heteromeric ...more Number of Targets: 22 |
| T3D3108 | Anabasine 13078-04-1 | C10H14N2 162.232 g/mol |  |
| Anabasine is a cholinesterase or acetylcholinesterase (AChE) inhibitor. A cholinesterase inhibitor (or 'anticholinesterase') suppresses the action of acetylcholinester...more Number of Targets: 16 |
| T3D0984 | Methomyl 16752-77-5 | C5H10N2O2S 162.210 g/mol |  |
| Methomyl is a cholinesterase or acetylcholinesterase (AChE) inhibitor. Carbamates form unstable complexes with chlolinesterases by carbamoylation of the active sites o...more Number of Targets: 5 |
| T3D4212 | Safrole 94-59-7 | C10H10O2 162.185 g/mol |  |
| Not Available Number of Targets: 2 |
| T3D1554 | Aluminum ethylate 555-75-9 | C6H15AlO3 162.163 g/mol |  |
| The main target organs of aluminum are the central nervous system and bone. Aluminum binds with dietary phosphorus and impairs gastrointestinal absorption of phosphoru...more Number of Targets: 3 |
| T3D4258 | 2-Hydroxyadipic acid 18294-85-4 | C6H10O5 162.141 g/mol |  |
| 2-Hydroxyadipic acid is a hydroxy-dicarboxylic acid formed by the reduction of 2-ketoadipic acid. Deficiency of 2-ketoadipic dehydrogenase causes 2-ketoadipic acidemia...more Number of Targets: 0 |
| T3D4262 | 3-Hydroxymethylglutaric acid 503-49-1 | C6H10O5 162.141 g/mol |  |
| Not Available Number of Targets: 1 |
| T3D1487 | Aluminium diacetate hydroxide 142-03-0 | C4H7AlO5 162.077 g/mol |  |
| The main target organs of aluminum are the central nervous system and bone. Aluminum binds with dietary phosphorus and impairs gastrointestinal absorption of phosphoru...more Number of Targets: 3 |
| T3D0290 | Potassium arsenite 10124-50-2 | AsKO3 162.018 g/mol |  |
| Arsenic and its metabolites disrupt ATP production through several mechanisms. At the level of the citric acid cycle, arsenic inhibits pyruvate dehydrogenase and by co...more Number of Targets: 44 |
| T3D0710 | Sodium chromate 7775-11-3 | CrNa2O4 161.973 g/mol |  |
| Hexavalent chromium's carcinogenic effects are caused by its metabolites, pentavalent and trivalent chromium. The DNA damage may be caused by hydroxyl radicals produce...more Number of Targets: 5 |
| T3D0309 | Methylarsonic acid, monosodium salt 2163-80-6 | CH4AsNaO3 161.952 g/mol |  |
| Arsenic and its metabolites disrupt ATP production through several mechanisms. At the level of the citric acid cycle, arsenic inhibits pyruvate dehydrogenase and by co...more Number of Targets: 44 |
| T3D0744 | Zinc sulfate 7733-02-0 | O4SZn 161.472 g/mol |  |
| Anaemia results from the excessive absorption of zinc suppressing copper and iron absorption, most likely through competitive binding of intestinal mucosal cells. Unba...more Number of Targets: 1 |
| T3D2958 | Bethanechol 674-38-4 | C7H17N2O2 161.222 g/mol |  |
| Bethanechol directly stimulates cholinergic receptors in the parasympathetic nervous system while stimulating the ganglia to a lesser extent. Its effects are predomina...more Number of Targets: 4 |
| T3D2832 | L-Carnitine 541-15-1 | C7H15NO3 161.199 g/mol |  |
| Levocarnitine can be synthesised within the body from the amino acids lysine or methionine. Vitamin C (ascorbic acid) is essential to the synthesis of carnitine. Levoc...more Number of Targets: 12 |
| T3D4259 | Aminoadipic acid 542-32-5 | C6H11NO4 161.156 g/mol |  |
| Not Available Number of Targets: 4 |
| T3D1311 | Methyldichloroarsine 593-89-5 | CH3AsCl2 160.862 g/mol |  |
| Arsenic and its metabolites disrupt ATP production through several mechanisms. At the level of the citric acid cycle, arsenic inhibits pyruvate dehydrogenase and by co...more Number of Targets: 45 |
| T3D1055 | (2E)-2-(Nitromethylidene)-1,3-thiazinane 58842-20-9 | C5H8N2O2S 160.194 g/mol |  |
| Acts as a neurotransmitter mimic , having both excitatory and depressant effects, eventually blocking postsynaptic nicotinic receptors. (T10) Number of Targets: 5 |
| T3D3821 | Daminozide 1596-84-5 | C6H12N2O3 160.171 g/mol |  |
| Not Available Number of Targets: 2 |
| T3D4257 | Oxoadipic acid 3184-35-8 | C6H8O5 160.125 g/mol |  |
| In the matrix of mitochondria, 2-oxoadipate is decarboxylated to glutaryl-CoA by the 2-oxoadipate dehydrogenase complex and then converted to acetyl-CoA. Accumulation ...more Number of Targets: 1 |
| T3D0317 | Sodium dimethylarsinate 124-65-2 | C2H6AsNaO2 159.979 g/mol |  |
| Arsenic and its metabolites disrupt ATP production through several mechanisms. At the level of the citric acid cycle, arsenic inhibits pyruvate dehydrogenase and by co...more Number of Targets: 44 |