Browsing Toxins
Displaying toxin 2751 - 2775 of 3678 in total
| T3DB ID | Name CAS Number | Formula Weight | Structure | Type | Mechanism of Toxicity |
|---|---|---|---|---|---|
| T3D2701 | Pyridoxine 65-23-6 | C8H11NO3 169.178 g/mol |  |
| Vitamin B6 is the collective term for a group of three related compounds, pyridoxine (PN), pyridoxal (PL) and pyridoxamine (PM), and their phosphorylated derivatives, ...more Number of Targets: 6 |
| T3D1185 | Chromated copper arsenate 37337-13-6 | AsCrCuH5O3 169.000 g/mol |  |
| Excess copper is sequestered within hepatocyte lysosomes, where it is complexed with metallothionein. Copper hepatotoxicity is believed to occur when the lysosomes bec...more Number of Targets: 49 |
| T3D0640 | Beryllium bromide 7787-46-4 | BeBr2 168.820 g/mol |  |
| Once in the body, beryllium acts as a hapten and interacts with human leucocyte antigen (HLA) DP presenting cells in the lungs, becoming physically associated with a m...more Number of Targets: 9 |
| T3D1059 | (2E)-2-(Nitromethylidene)-1-prop-2-enylpyrrolidine 40990-27-0 | C8H12N2O2 168.193 g/mol |  |
| Acts as a neurotransmitter mimic , having both excitatory and depressant effects, eventually blocking postsynaptic nicotinic receptors. (T10) Number of Targets: 5 |
| T3D1661 | Hexamethylene diisocyanate 822-06-0 | C8H12N2O2 168.193 g/mol |  |
| Cyanide is an inhibitor of cytochrome c oxidase in the fourth complex of the electron transport chain (found in the membrane of the mitochondria of eukaryotic cells). ...more Number of Targets: 40 |
| T3D5004 | Quinolacetic acid 55604-87-0 | C8H8O4 168.148 g/mol |  | Not Available | Not Available Number of Targets: 0 |
| T3D4989 | 3-Acetyl-4-hydroxy-6-methyl-2H-pyran-2-one 771-03-9 | C8H8O4 168.147 g/mol |  |
| Not Available Number of Targets: 0 |
| T3D4287 | Homogentisic acid 451-13-8 | C8H8O4 168.147 g/mol |  |
| Extremely high levels of homogentisic acid are found in patients with the inborn error of metabolism (IEM) called Alkaptonuria. Homogentisic acid spontaneously undergo...more Number of Targets: 0 |
| T3D3013 | Desflurane 57041-67-5 | C3H2F6O 168.038 g/mol |  |
| Desflurane induces a reduction in junctional conductance by decreasing gap junction channel opening times and increasing gap junction channel closing times. Desflurane...more Number of Targets: 8 |
| T3D1455 | Chromium chromate 41261-95-4 | Cr2O4 167.990 g/mol |  |
| Hexavalent chromium's carcinogenic effects are caused by its metabolites, pentavalent and trivalent chromium. The DNA damage may be caused by hydroxyl radicals produce...more Number of Targets: 5 |
| T3D0146 | 1,1,2,2-Tetrachloroethane 79-34-5 | C2H2Cl4 167.849 g/mol |  |
| The presence of the functional group consisting of a terminal dichloromethyl moiety in a molecule is known to confer toxicity. Moreover, the metabolism of 1,1,2,2-tetr...more Number of Targets: 39 |
| T3D4857 | 2(3H)-Benzothiazolethione 149-30-4 | C7H5NS2 167.251 g/mol |  |
| Not Available Number of Targets: 3 |
| T3D2963 | Ethinamate 126-52-3 | C9H13NO2 167.205 g/mol |  |
| The mechanism of action is not known. However, studies have shown that ethinamate inhibits carbonic anhydrases I and II (J Biol Chem. 1992 Dec 15;267(35):25044-50). Th...more Number of Targets: 2 |
| T3D4770 | Tioguanine 154-42-7 | C5H5N5S 167.192 g/mol |  |
| Thioguanine competes with hypoxanthine and guanine for the enzyme hypoxanthine-guanine phosphoribosyltransferase (HGPRTase) and is itself converted to 6-thioguanilyic ...more Number of Targets: 6 |
| T3D1045 | 2-[(2E)-2-(Nitromethylidene)pyrrolidin-1-yl]acetonitrile 1164504-23-7 | C7H9N3O2 167.165 g/mol |  |
| Acts as a neurotransmitter mimic , having both excitatory and depressant effects, eventually blocking postsynaptic nicotinic receptors. (T10) Organic nitriles decompos...more Number of Targets: 5 |
| T3D1064 | [2-(Nitromethylene)-1-pyrrolidinyl]acetonitrile 91417-82-2 | C7H9N3O2 167.165 g/mol |  |
| Acts as a neurotransmitter mimic , having both excitatory and depressant effects, eventually blocking postsynaptic nicotinic receptors. (T10) Organic nitriles decompo...more Number of Targets: 5 |
| T3D0898 | 2-Hydroxyphenyl methylcarbamate 10309-97-4 | C8H9NO3 167.162 g/mol |  |
| 2-Hydroxyphenyl methylcarbamate is a cholinesterase or acetylcholinesterase (AChE) inhibitor. Carbamates form unstable complexes with chlolinesterases by carbamoylatio...more Number of Targets: 2 |
| T3D1799 | Ethyl bromoacetate 105-36-2 | C4H7BrO2 167.001 g/mol |  |
| Bromine is a powerful oxidizing agent and is able to release oxygen free radicals from the water in mucous membranes. These free radicals are also potent oxidizers and...more Number of Targets: 1 |
| T3D1716 | Potassium bromate 7758-01-2 | BrKO3 167.001 g/mol |  |
| Bromine is a powerful oxidizing agent and is able to release oxygen free radicals from the water in mucous membranes. These free radicals are also potent oxidizers and...more Number of Targets: 6 |
| T3D1599 | Silver acetate 563-63-3 | C2H3AgO2 166.912 g/mol |  |
| Metallic silver is oxidized and may deposit in the tissues, causing arygria. The silver ion is known to inhibit glutathione peroxidase and NA+,K+-ATPase activity, disr...more Number of Targets: 17 |
| T3D1376 | Zinc beryllium silicate 39413-47-3 | BeO4SiZn 166.504 g/mol |  |
| Anaemia results from the excessive absorption of zinc suppressing copper and iron absorption, most likely through competitive binding of intestinal mucosal cells. Unba...more Number of Targets: 4 |
| T3D0625 | Fluorene 86-73-7 | C13H10 166.219 g/mol |  |
| The ability of PAH's to bind to blood proteins such as albumin allows them to be transported throughout the body. Many PAH's induce the expression of cytochrome P450 e...more Number of Targets: 3 |
| T3D4859 | 2-tert-Butyl-1,4-benzenediol 1948-33-0 | C10H14O2 166.217 g/mol |  |
| Not Available Number of Targets: 7 |
| T3D3230 | 2-Methoxy-4-propylphenol 2785-87-7 | C10H14O2 166.217 g/mol |  |
| Dihydroeugenol may cause allergic contact dermatitis via two different mechanisms: The poison ivy and the phenolic radical mechanisms (A2445). Number of Targets: 1 |
| T3D4493 | Cyromazine 66215-27-8 | C6H10N6 166.184 g/mol |  |
| Not Available Number of Targets: 3 |