Browsing Toxins
| T3DB ID | Name CAS Number | Formula Weight | Structure | Type | Mechanism of Toxicity |
|---|---|---|---|---|---|
| T3D0782 | 1,3-Dinitrobenzene 99-65-0 | C6H6N4O4 198.136 g/mol |  |
| In the red blood cell, 1,3-DNB induces formation of methemoglobin, leading to cyanosis. Reduction of the nitrogroup(s) of 1,3-DNB produces reactive nitroaromatic radic...more Number of Targets: 9 |
| T3D2211 | 1,4,6,7-Tetrachlorodibenzofuran 66794-59-0 | C12H4Cl4O 305.972 g/mol |  |
| Halogenated dibenzofurans (PCDFs and PBDFs) bind the aryl hydrocarbon receptor (AhR), which increases its ability to activate transcription in the XRE (xenobiotic reso...more Number of Targets: 2 |
| T3D2212 | 1,4,6,8-Tetrachlorodibenzofuran 82911-58-8 | C12H4Cl4O 305.972 g/mol |  |
| Halogenated dibenzofurans (PCDFs and PBDFs) bind the aryl hydrocarbon receptor (AhR), which increases its ability to activate transcription in the XRE (xenobiotic reso...more Number of Targets: 2 |
| T3D2090 | 1,4,6,9-Tetrachlorodibenzo-p-dioxin 40581-93-9 | C12H4Cl4O2 321.971 g/mol |  |
| CDDs cause their toxic effects by binding to the aryl hydrocarbon receptor and subsequently altering the trascription of certain genes. The affinity for the Ah recepto...more Number of Targets: 4 |
| T3D2446 | 1,4,6,9-Tetrachlorodibenzofuran 70648-19-0 | C12H4Cl4O 305.972 g/mol |  |
| Halogenated dibenzofurans (PCDFs and PBDFs) bind the aryl hydrocarbon receptor (AhR), which increases its ability to activate transcription in the XRE (xenobiotic reso...more Number of Targets: 2 |
| T3D2432 | 1,4,6-Trichlorodibenzofuran 82911-60-2 | C12H5Cl3O 271.527 g/mol |  |
| Halogenated dibenzofurans (PCDFs and PBDFs) bind the aryl hydrocarbon receptor (AhR), which increases its ability to activate transcription in the XRE (xenobiotic reso...more Number of Targets: 2 |
| T3D2091 | 1,4,7,8-Tetrachlorodibenzo-p-dioxin 40581-94-0 | C12H4Cl4O2 321.971 g/mol |  |
| CDDs cause their toxic effects by binding to the aryl hydrocarbon receptor and subsequently altering the trascription of certain genes. The affinity for the Ah recepto...more Number of Targets: 4 |
| T3D2213 | 1,4,7,8-Tetrachlorodibenzofuran 83704-29-4 | C12H4Cl4O 305.972 g/mol |  |
| Halogenated dibenzofurans (PCDFs and PBDFs) bind the aryl hydrocarbon receptor (AhR), which increases its ability to activate transcription in the XRE (xenobiotic reso...more Number of Targets: 2 |
| T3D2433 | 1,4,7-Trichlorodibenzofuran 83704-41-0 | C12H5Cl3O 271.527 g/mol |  |
| Halogenated dibenzofurans (PCDFs and PBDFs) bind the aryl hydrocarbon receptor (AhR), which increases its ability to activate transcription in the XRE (xenobiotic reso...more Number of Targets: 2 |
| T3D2063 | 1,4,8-Trichlorodibenzo-p-dioxin 82306-64-7 | C12H5Cl3O2 287.526 g/mol |  |
| CDDs cause their toxic effects by binding to the aryl hydrocarbon receptor and subsequently altering the trascription of certain genes. The affinity for the Ah recepto...more Number of Targets: 4 |
| T3D2214 | 1,4,8-Trichlorodibenzofuran 64560-14-1 | C12H5Cl3O 271.527 g/mol |  |
| Halogenated dibenzofurans (PCDFs and PBDFs) bind the aryl hydrocarbon receptor (AhR), which increases its ability to activate transcription in the XRE (xenobiotic reso...more Number of Targets: 2 |
| T3D2062 | 1,4,9-Trichlorodibenzo-p-dioxin 82306-63-6 | C12H5Cl3O2 287.526 g/mol |  |
| CDDs cause their toxic effects by binding to the aryl hydrocarbon receptor and subsequently altering the trascription of certain genes. The affinity for the Ah recepto...more Number of Targets: 4 |
| T3D2434 | 1,4,9-Trichlorodibenzofuran 70648-13-4 | C12H5Cl3O 271.527 g/mol |  |
| Halogenated dibenzofurans (PCDFs and PBDFs) bind the aryl hydrocarbon receptor (AhR), which increases its ability to activate transcription in the XRE (xenobiotic reso...more Number of Targets: 2 |
| T3D0159 | 1,4-Dichlorobenzene 106-46-7 | C6H4Cl2 147.002 g/mol |  |
| The hepatotoxicity and nephrotoxicity observed in laboratory animals are likely due to the formation of toxic intermediates formed while converting 1,4-DCB to 2,5-dich...more Number of Targets: 40 |
| T3D2053 | 1,4-Dichlorodibenzo-p-dioxin 54536-19-5 | C12H6Cl2O2 253.081 g/mol |  |
| CDDs cause their toxic effects by binding to the aryl hydrocarbon receptor and subsequently altering the trascription of certain genes. The affinity for the Ah recepto...more Number of Targets: 4 |
| T3D2415 | 1,4-Dichlorodibenzofuran 94538-01-9 | C12H6Cl2O 237.081 g/mol |  |
| Halogenated dibenzofurans (PCDFs and PBDFs) bind the aryl hydrocarbon receptor (AhR), which increases its ability to activate transcription in the XRE (xenobiotic reso...more Number of Targets: 2 |
| T3D0210 | 1,4-Dioxane 123-91-1 | C4H8O2 88.105 g/mol |  |
| Though the mechanism of toxicity of 1,4-dioxane has not yet been elucidated, it is known that its carcinogenic effects are caused by a non-genotoxic mechanism that is ...more Number of Targets: 4 |
| T3D4637 | 1,4-Naphthoquinone 130-15-4 | C10H6O2 158.153 g/mol |  |
| Not Available Number of Targets: 5 |
| T3D2049 | 1,6-Dichlorodibenzo-p-dioxin 38178-38-0 | C12H6Cl2O2 253.081 g/mol |  |
| CDDs cause their toxic effects by binding to the aryl hydrocarbon receptor and subsequently altering the trascription of certain genes. The affinity for the Ah recepto...more Number of Targets: 4 |
| T3D2416 | 1,6-Dichlorodibenzofuran 74992-97-5 | C12H6Cl2O 237.081 g/mol |  |
| Halogenated dibenzofurans (PCDFs and PBDFs) bind the aryl hydrocarbon receptor (AhR), which increases its ability to activate transcription in the XRE (xenobiotic reso...more Number of Targets: 2 |
| T3D2061 | 1,7,8-Trichlorodibenzo-p-dioxin 82306-65-8 | C12H5Cl3O2 287.526 g/mol |  |
| CDDs cause their toxic effects by binding to the aryl hydrocarbon receptor and subsequently altering the trascription of certain genes. The affinity for the Ah recepto...more Number of Targets: 4 |
| T3D2057 | 1,7-Dichlorodibenzo-p-dioxin 82291-26-7 | C12H6Cl2O2 253.081 g/mol |  |
| CDDs cause their toxic effects by binding to the aryl hydrocarbon receptor and subsequently altering the trascription of certain genes. The affinity for the Ah recepto...more Number of Targets: 4 |
| T3D2417 | 1,7-Dichlorodibenzofuran 94538-02-0 | C12H6Cl2O 237.081 g/mol |  |
| Halogenated dibenzofurans (PCDFs and PBDFs) bind the aryl hydrocarbon receptor (AhR), which increases its ability to activate transcription in the XRE (xenobiotic reso...more Number of Targets: 2 |
| T3D2056 | 1,8-Dichlorodibenzo-p-dioxin 82291-27-8 | C12H6Cl2O2 253.081 g/mol |  |
| CDDs cause their toxic effects by binding to the aryl hydrocarbon receptor and subsequently altering the trascription of certain genes. The affinity for the Ah recepto...more Number of Targets: 4 |
| T3D2418 | 1,8-Dichlorodibenzofuran 81638-37-1 | C12H6Cl2O 237.081 g/mol |  |
| Halogenated dibenzofurans (PCDFs and PBDFs) bind the aryl hydrocarbon receptor (AhR), which increases its ability to activate transcription in the XRE (xenobiotic reso...more Number of Targets: 2 |