Browsing Toxins By Category
| T3DB ID | Name CAS Number | Formula Weight | Structure | Type | Mechanism of Toxicity |
|---|---|---|---|---|---|
| T3D3268 | Acetic acid 64-19-7 | C2H3O2 59.045 g/mol |  |
| Acetic acid is toxic due to its corrosive nature. In addition to causing skin burns and irritation to the mucous membranes, ingestion can result in severe damage to th...more Number of Targets: 4 |
| T3D4209 | Acetamide 60-35-5 | C2H5NO 59.067 g/mol |  |
| Not Available Number of Targets: 1 |
| T3D4172 | Guanidine 113-00-8 | CH5N3 59.071 g/mol |  |
| Uremic toxins such as guaniidine are actively transported into the kidneys via organic ion transporters (especially OAT3). Increased levels of uremic toxins can stimul...more Number of Targets: 8 |
| T3D4163 | Trimethylamine 75-50-3 | C3H9N 59.110 g/mol |  |
| Uremic toxins such as trimethylamine are actively transported into the kidneys via organic ion transporters (especially OAT3). Increased levels of uremic toxins can st...more Number of Targets: 3 |
| T3D4973 | Cobalt-60 10198-40-0 | Co 59.934 g/mol |  |
| Cobalt is believed to exhibit its toxicity through a oxidant-based and free radical-based processes. It produces oxygen radicals and may be oxidized to ionic cobalt, c...more Number of Targets: 38 |
| T3D1568 | gamma-Aluminum oxide hydroxide 1318-23-6 | AlHO2 59.988 g/mol |  |
| The main target organs of aluminum are the central nervous system and bone. Aluminum binds with dietary phosphorus and impairs gastrointestinal absorption of phosphoru...more Number of Targets: 3 |
| T3D4699 | Isopropyl alcohol 67-63-0 | C3H8O 60.095 g/mol |  |
| Not Available Number of Targets: 16 |
| T3D4202 | Carbamic acid 463-77-4 | CH3NO2 61.040 g/mol |  |
| Carbamic acid is a cholinesterase or acetylcholinesterase (AChE) inhibitor. A cholinesterase inhibitor (or 'anticholinesterase') suppresses the action of acetylcholine...more Number of Targets: 1 |
| T3D4769 | Ethanolamine 141-43-5 | C2H7NO 61.083 g/mol |  |
| Not Available Number of Targets: 4 |
| T3D0756 | Cyanogen chloride 506-77-4 | CClN 61.470 g/mol |  |
| Organic nitriles decompose into cyanide ions both in vivo and in vitro. Consequently the primary mechanism of toxicity for organic nitriles is their production of toxi...more Number of Targets: 39 |
| T3D3799 | Boric acid (H3BO3) 10043-35-3 | BH3O3 61.833 g/mol |  |
| Not Available Number of Targets: 4 |
| T3D0216 | Nitrate 14797-55-8 | NO3 62.005 g/mol |  |
| Nitrate's toxicity is a result of it's conversion to nitrite once in the body. Nitrite causes the autocatalytic oxidation of oxyhemoglobin to hydrogen peroxide and met...more Number of Targets: 16 |
| T3D0772 | Ethylene glycol 107-21-1 | C2H6O2 62.068 g/mol |  |
| Ethylene glycol is metabolized by alcohol dehydrogenase to glycoaldehyde, which is then metabolized to glycolic, glyoxylic, and oxalic acids. These acids, along with e...more Number of Targets: 0 |
| T3D1512 | Aluminium monochloride 13595-81-8 | AlCl 62.435 g/mol |  |
| The main target organs of aluminum are the central nervous system and bone. Aluminum binds with dietary phosphorus and impairs gastrointestinal absorption of phosphoru...more Number of Targets: 3 |
| T3D0004 | Vinyl chloride 75-01-4 | C2H3Cl 62.498 g/mol |  |
| Vinyl chloride poisoning exhibits many of the characteristics of autoimmune diseases. This is believed to be the result of a reactive vinyl chloride intermediate metab...more Number of Targets: 43 |
| T3D3571 | Nitric acid 7697-37-2 | HNO3 63.013 g/mol |  |
| Nitric acid is a corrosive acid and a powerful oxidizing agent. The major hazard posed by it is chemical burns as it carries out acid hydrolysis with proteins (amide) ...more Number of Targets: 16 |
| T3D0128 | Copper 7440-50-8 | Cu 63.545 g/mol |  |
| Excess copper is sequestered within hepatocyte lysosomes, where it is complexed with metallothionein. Copper hepatotoxicity is believed to occur when the lysosomes bec...more Number of Targets: 20 |
| T3D3548 | Ammonium nitrite 13446-48-5 | H4N2O2 64.044 g/mol |  |
| Nitrite causes the autocatalytic oxidation of oxyhemoglobin to hydrogen peroxide and methemoglobin. This elevation of methemoglobin levels is a condition known as meth...more Number of Targets: 9 |
| T3D0183 | Chloroethane 75-00-3 | C2H5Cl 64.514 g/mol |  |
| Chloroethane targets the central nervous system and the heart. The lipophilicity of chloroethane suggests it acts upon the lipid layer of cellular membrane or the hydr...more Number of Targets: 2 |
| T3D1626 | Vanadium nitride 24646-85-3 | NV 64.948 g/mol |  |
| Vanadium damages alveolar macrophages by decreasing the macrophage membrane integrity, thus impairing the cells' phagocytotic ability and viability. The pentavalent fo...more Number of Targets: 47 |
| T3D0761 | Potassium cyanide 151-50-8 | CKN 65.116 g/mol |  |
| Organic nitriles decompose into cyanide ions both in vivo and in vitro. Consequently the primary mechanism of toxicity for organic nitriles is their production of toxi...more Number of Targets: 42 |
| T3D0074 | Zinc 7440-66-6 | Zn 65.408 g/mol |  |
| Excessive zinc intake alters copper and iron absorption, most likely through competitive binding in intestinal mucosal cells. Stomach acid dissolves metallic zinc, pro...more Number of Targets: 28 |
| T3D1538 | Lithium aluminate 12003-67-7 | AlLiO2 65.921 g/mol |  |
| The main target organs of aluminum are the central nervous system and bone. Aluminum binds with dietary phosphorus and impairs gastrointestinal absorption of phosphoru...more Number of Targets: 3 |
| T3D1434 | Chromium nitride 24094-93-7 | CrN 66.003 g/mol |  |
| Trivalent chromium may also form complexes with peptides, proteins, and DNA, resulting in DNA-protein crosslinks, DNA strand breaks, DNA-DNA interstrand crosslinks, ch...more Number of Targets: 5 |
| T3D1704 | Malononitrile 109-77-3 | C3H2N2 66.061 g/mol |  |
| Organic nitriles decompose into cyanide ions both in vivo and in vitro. Consequently the primary mechanism of toxicity for organic nitriles is their production of toxi...more Number of Targets: 39 |