Browsing Toxins By Category
| T3DB ID | Name CAS Number | Formula Weight | Structure | Type | Mechanism of Toxicity |
|---|---|---|---|---|---|
| T3D0770 | Ethanol 64-17-5 | C2H6O 46.068 g/mol |  |
| Alcohol binds to the GABA(A) receptors (delta subunit), NMDA receptors, Glycine receptors, Serotonin receptors, Acetylcholine receptors, L-channel calcium channels and...more Number of Targets: 67 |
| T3D0644 | Beryllium fluoride 7787-49-7 | BeF2 47.009 g/mol |  |
| Once in the body, beryllium acts as a hapten and interacts with human leucocyte antigen (HLA) DP presenting cells in the lungs, becoming physically associated with a m...more Number of Targets: 3 |
| T3D3549 | Nitrous acid 7782-77-6 | HNO2 47.013 g/mol |  |
| Nitrite causes the autocatalytic oxidation of oxyhemoglobin to hydrogen peroxide and methemoglobin. This elevation of methemoglobin levels is a condition known as meth...more Number of Targets: 9 |
| T3D4725 | Ozone 10028-15-6 | O3 47.998 g/mol |  |
| Ozone is a strong oxidant and reacts directly with organic double bonds. When ozone breaks down to dioxygen it gives rise to oxygen free radicals, which are highly rea...more Number of Targets: 1 |
| T3D0766 | Sodium cyanide 143-33-9 | CNNa 49.007 g/mol |  |
| Organic nitriles decompose into cyanide ions both in vivo and in vitro. Consequently the primary mechanism of toxicity for organic nitriles is their production of toxi...more Number of Targets: 42 |
| T3D0198 | Vanadium 7440-62-2 | V 50.940 g/mol |  |
| Vanadium damages alveolar macrophages by decreasing the macrophage membrane integrity, thus impairing the cell's phagocytotic ability and viability. The pentavalent fo...more Number of Targets: 47 |
| T3D0077 | Chromium 7440-47-3 | Cr 51.993 g/mol |  |
| Hexavalent chromium's carcinogenic effects are caused by its metabolites, pentavalent and trivalent chromium. The DNA damage may be caused by hydroxyl radicals produce...more Number of Targets: 6 |
| T3D0018 | Hexavalent chromium 18540-29-9 | Cr 51.996 g/mol |  |
| Hexavalent chromium's carcinogenic effects are caused by its metabolites, pentavalent and trivalent chromium. The DNA damage may be caused by hydroxyl radicals produce...more Number of Targets: 5 |
| T3D0754 | Cyanogen 460-19-5 | C2N2 52.035 g/mol |  |
| Organic nitriles decompose into cyanide ions both in vivo and in vitro. Consequently the primary mechanism of toxicity for organic nitriles is their production of toxi...more Number of Targets: 39 |
| T3D1688 | Acrylonitrile 107-13-1 | C3H3N 53.063 g/mol |  |
| Organic nitriles decompose into cyanide ions both in vivo and in vitro. Consequently the primary mechanism of toxicity for organic nitriles is their production of toxi...more Number of Targets: 39 |
| T3D1532 | Sodium aluminium hydride 13770-96-2 | AlH4Na 54.003 g/mol |  |
| The main target organs of aluminum are the central nervous system and bone. Aluminum binds with dietary phosphorus and impairs gastrointestinal absorption of phosphoru...more Number of Targets: 3 |
| T3D0156 | 1,3-Butadiene 106-99-0 | C4H6 54.090 g/mol |  |
| Certain metabolites of 1,3-butadiene have been shown to bind to DNA and nucleoproteins, forming protein-DNA and DNA-DNA crosslinks. Specifically, 1,2-epoxybutene-3 and...more Number of Targets: 2 |
| T3D0117 | Manganese 7439-96-5 | Mn 54.937 g/mol |  |
| Manganese is a cellular toxicant that can impair transport systems, enzyme activities, and receptor functions. It primarily targets the central nervous system, particu...more Number of Targets: 10 |
| T3D1708 | Propionitrile 107-12-0 | C3H5N 55.079 g/mol |  |
| Organic nitriles decompose into cyanide ions both in vivo and in vitro. Consequently the primary mechanism of toxicity for organic nitriles is their production of toxi...more Number of Targets: 39 |
| T3D4697 | Iron 7439-89-6 | Fe 55.845 g/mol |  |
| Iron is necessary for the production of hemoglobin. Iron-deficiency can lead to decreased production of hemoglobin and a microcytic, hypochromic anemia. Number of Targets: 0 |
| T3D0037 | Acrolein 107-02-8 | C3H4O 56.063 g/mol |  |
| Acrolein rapidly and irreversibly binds to lysine moieties and sulfhydryl groups found on many cellular molecules forming thiol ethers. By this mechanism acrolein can ...more Number of Targets: 29 |
| T3D1663 | Methyl isocyanate 624-83-9 | C2H3NO 57.051 g/mol |  |
| Cyanide is an inhibitor of cytochrome c oxidase in the fourth complex of the electron transport chain (found in the membrane of the mitochondria of eukaryotic cells). ...more Number of Targets: 40 |
| T3D1520 | Aluminium phosphide 20859-73-8 | AlP 57.955 g/mol |  |
| The main target organs of aluminum are the central nervous system and bone. Aluminum binds with dietary phosphorus and impairs gastrointestinal absorption of phosphoru...more Number of Targets: 23 |
| T3D0184 | Acetone 67-64-1 | C3H6O 58.079 g/mol |  |
| Since acetone is highly water soluble, it is readily taken up by the blood and widely distributed to body tissues. Acetone may interfere with the composition of the me...more Number of Targets: 1 |
| T3D0089 | Thiocyanate 302-04-5 | CNS 58.083 g/mol |  |
| Thiocyanate (sulphocyanate or SCN) is believed to be a goitrogenic compound. It is a competitive inhibitor of the human thyroid sodium/iodide symporter NIS. Thus, the ...more Number of Targets: 8 |
| T3D3426 | n-Butane 106-97-8 | C4H10 58.122 g/mol |  |
| Butane is a simple asphyxiant and causes toxicity by displacing oxygen. It also affects the central nervous system by enhancing glycine receptors and inhibiting N-meth...more Number of Targets: 0 |
| T3D3427 | Isobutane 75-28-5 | C4H10 58.122 g/mol |  |
| Butane is a simple asphyxiant and causes toxicity by displacing oxygen. It also affects the central nervous system by enhancing glycine receptors and inhibiting nicoti...more Number of Targets: 28 |
| T3D4666 | Sodium chloride 7647-14-5 | ClNa 58.443 g/mol |  |
| A high salt diet disrupts the natural sodium balance in the body. This causes fluid retention which increases the pressure exerted by the blood against blood vessel wa...more Number of Targets: 22 |
| T3D0053 | Nickel 7440-02-0 | Ni 58.692 g/mol |  |
| Nickel is known to substitute for other essential elements in certain enzmes, such as calcineurin. It is genotoxic, and some nickel compounds have been shown to promot...more Number of Targets: 73 |
| T3D0049 | Cobalt 7440-48-4 | Co 58.932 g/mol |  |
| Cobalt is believed to exhibit its toxicity through a oxidant-based and free radical-based processes. It produces oxygen radicals and may be oxidized to ionic cobalt, c...more Number of Targets: 38 |