Browsing Toxins By Category
| T3DB ID | Name CAS Number | Formula Weight | Structure | Type | Mechanism of Toxicity |
|---|---|---|---|---|---|
| T3D2643 | Vipoxin Not Available | Not Available 13827.665 g/mol |  |
| Vipoxin inhibits the binding of ligands to biogenic amine receptors including dopamine,
serotonin and alpha1/alpha2 adrenergic receptors. Vipoxin also exhibits hemoly...more Number of Targets: 28 |
| T3D2646 | Hydralysin (Chlorohydra viridissima) Not Available | Not Available 26212.075 g/mol |  |
| Hydralysin is a cytolytic toxin. It binds to erythrocyte membranes and has weak hemolytic activity, probably mediated by oligomerization and pore formation. (T170) Number of Targets: 0 |
| T3D2647 | Stonustoxin Not Available | Not Available 79523.640 g/mol | |
| Stonustoxin induces hemolytic activities due to its ability to form pores in the cell membrane. It is also myotoxic and interferes irreversibly with neuromuscular func...more Number of Targets: 0 |
| T3D2648 | Neoverrucotoxin Not Available | Not Available 79669.850 g/mol | |
| Neoverrucotoxin has hemolytic activities. (T170) Number of Targets: 0 |
| T3D2649 | Box jellyfish toxin (Chironex fleckeri) Not Available | Not Available 51389.865 g/mol | |
| Box jellyfish toxin has potent hemolytic activity and may act as a pore-forming toxin, disrupting normal transmembrane ion concentration gradients in susceptible cells...more Number of Targets: 0 |
| T3D2656 | omega-Conotoxin (Conus striatus) Not Available | Not Available 7628.040 g/mol |  |
| omega-Conotoxins act at presynaptic membranes, where they bind inhibit N-type voltage-dependent calcium channels. (L1107) Number of Targets: 1 |
| T3D2657 | alpha-Conotoxin (Conus geographus) Not Available | Not Available 1627.830 g/mol |  |
| alpha-Conotoxins act on postsynaptic membranes, where they inhibit nicotinic acetylcholine receptors in nerves and muscles. (L1107) Number of Targets: 15 |
| T3D2658 | delta-Conotoxin (Conus striatus) Not Available | Not Available 9216.755 g/mol |  |
| delta-Conotoxins inhibit the inactivation of voltage-dependent sodium channels. (L1107) Number of Targets: 14 |
| T3D2659 | kappa-Conotoxin (Conus purpurascens) Not Available | Not Available 8316.795 g/mol |  |
| kappa-Conotoxins inhibit potassium channels. (L1107) Number of Targets: 23 |
| T3D2660 | mu-Conotoxin (Conus purpurascens) Not Available | Not Available 8333.700 g/mol |  |
| mu-Conotoxins inhibit voltage-dependent sodium channels in muscles. (L1107) Number of Targets: 14 |
| T3D2661 | Contryphan (Conus ventricosus) Not Available | Not Available 1091.260 g/mol |  |
| Contryphan affects both voltage-gated and calcium-dependent potassium channels. (L1108) Number of Targets: 32 |
| T3D2671 | Rituximab 174722-31-7 | Not Available 36105.695 g/mol |  |
| Binds to the CD20 antigen which is found on mature B lymphocytes. The Fc domain recruits immune effector functions to mediate B-cell lysis. The antibody appears to ind...more Number of Targets: 12 |
| T3D3070 | Abrin-a 53597-23-2 | Not Available 59243.125 g/mol |  |
| Abrin works by penetrating the cells of the body and inhibiting cell protein synthesis. By attaching to a carbohydrate chain on the cell surface, the abrin molecule an...more Number of Targets: 1 |
| T3D3071 | Abrin-b Not Available | Not Available 59114.060 g/mol |  |
| Abrin works by penetrating the cells of the body and inhibiting cell protein synthesis. By attaching to a carbohydrate chain on the cell surface, the abrin molecule an...more Number of Targets: 1 |
| T3D3072 | Abrin-c 53597-24-3 | Not Available 62817.245 g/mol |  |
| Abrin works by penetrating the cells of the body and inhibiting cell protein synthesis. By attaching to a carbohydrate chain on the cell surface, the abrin molecule an...more Number of Targets: 1 |
| T3D3073 | Abrin-d 1393-62-0 | Not Available 58869.605 g/mol |  |
| Abrin works by penetrating the cells of the body and inhibiting cell protein synthesis. By attaching to a carbohydrate chain on the cell surface, the abrin molecule an...more Number of Targets: 1 |
| T3D3088 | Thionin (Pyrularia pubera) Not Available | Not Available 5288.110 g/mol |  |
| Thionins are thought to attack the cell membrane and render it permeable. This results in the inhibition of sugar uptake and allows potassium and phosphate ions, prote...more Number of Targets: 0 |
| T3D3121 | Diphtheria toxin (Corynephage omega) Not Available | Not Available 60814.155 g/mol |  |
| Diphtheria toxin consists of a single polypeptide. Proteolysis yields two fragments (A and B) which are held together by a disulfide bond. The toxin binds to EGF-like ...more Number of Targets: 1 |
| T3D3123 | Botulinum neurotoxin type E Not Available | Not Available 143842.990 g/mol |  |
| Botulinum toxin is a two-chain polypeptide with a 100-kDa heavy chain joined by a disulfide bond to a 50-kDa light chain. Following the attachment of the toxin heavy c...more Number of Targets: 0 |
| T3D3124 | Botulinum neurotoxin type F Not Available | Not Available 146708.095 g/mol |  |
| Botulinum toxin is a two-chain polypeptide with a 100-kDa heavy chain joined by a disulfide bond to a 50-kDa light chain. Following the attachment of the toxin heavy c...more Number of Targets: 0 |
| T3D3125 | Botulinum neurotoxin type B Not Available | Not Available 150801.160 g/mol |  |
| Botulinum toxin is a two-chain polypeptide with a 100-kDa heavy chain joined by a disulfide bond to a 50-kDa light chain. Following the attachment of the toxin heavy c...more Number of Targets: 0 |
| T3D3126 | Botulinum neurotoxin type D Not Available | Not Available 146871.005 g/mol |  |
| Botulinum toxin is a two-chain polypeptide with a 100-kDa heavy chain joined by a disulfide bond to a 50-kDa light chain. Following the attachment of the toxin heavy c...more Number of Targets: 0 |
| T3D3127 | Botulinum neurotoxin type A Not Available | Not Available 149452.615 g/mol |  |
| Botulinum toxin is a two-chain polypeptide with a 100-kDa heavy chain joined by a disulfide bond to a 50-kDa light chain. Following the attachment of the toxin heavy c...more Number of Targets: 0 |
| T3D3128 | Botulinum neurotoxin type C1 Not Available | Not Available 143395.640 g/mol |  |
| Botulinum toxin is a two-chain polypeptide with a 100-kDa heavy chain joined by a disulfide bond to a 50-kDa light chain. Following the attachment of the toxin heavy c...more Number of Targets: 0 |
| T3D3129 | Shiga toxin subunit B 75757-64-1 | Not Available 9743.070 g/mol |  |
| Shiga toxin causes the glycosidase cleavage of ribosomal eucaryotic 28S rRNA, resulting in inhibition of protein synthesis in susceptible cells. (L1767) Number of Targets: 1 |