Browsing Toxins By Category
Displaying toxin 426 - 450 of 3678 in total
| T3DB ID | Name CAS Number | Formula Weight | Structure | Type | Mechanism of Toxicity |
|---|---|---|---|---|---|
| T3D0728 | Zinc fluoride 7783-49-5 | F2Zn 103.406 g/mol |  |
| Anaemia results from the excessive absorption of zinc suppressing copper and iron absorption, most likely through competitive binding of intestinal mucosal cells. Unba...more Number of Targets: 1 |
| T3D4269 | 4-Hydroxybutyric acid 591-81-1 | C4H8O3 104.105 g/mol |  |
| GHB reaches much higher concentrations in the brain and activates GABAB receptors, which are primarily responsible for its sedative effects. GHB receptors are densely ...more Number of Targets: 2 |
| T3D0271 | Styrene 100-42-5 | C8H8 104.149 g/mol |  |
| Styrene 7,8-oxide, a metabolite of styrene, can form DNA adducts by binding to deoxyguanosine. It is also mutagenic and causes increased frequency of sister chromatid ...more Number of Targets: 1 |
| T3D0650 | Beryllium phosphate 13598-15-7 | BeHO4P 104.992 g/mol |  |
| Once in the body, beryllium acts as a hapten and interacts with human leucocyte antigen (HLA) DP presenting cells in the lungs, becoming physically associated with a m...more Number of Targets: 3 |
| T3D0652 | Beryllium sulfate 13510-49-1 | BeO4S 105.075 g/mol |  |
| Once in the body, beryllium acts as a hapten and interacts with human leucocyte antigen (HLA) DP presenting cells in the lungs, becoming physically associated with a m...more Number of Targets: 3 |
| T3D4367 | L-Serine 56-45-1 | C3H7NO3 105.093 g/mol |  |
| L-Serine plays a role in cell growth and development (cellular proliferation). The conversion of L-serine to glycine by serine hydroxymethyltransferase results in the ...more Number of Targets: 8 |
| T3D4845 | Diethanolamine 111-42-2 | C4H11NO2 105.136 g/mol |  |
| Not Available Number of Targets: 1 |
| T3D0755 | Cyanogen bromide 506-68-3 | CBrN 105.921 g/mol |  |
| Organic nitriles decompose into cyanide ions both in vivo and in vitro. Consequently the primary mechanism of toxicity for organic nitriles is their production of toxi...more Number of Targets: 45 |
| T3D0304 | Dimethylarsine 593-57-7 | C2H7As 105.999 g/mol |  |
| Arsenic and its metabolites disrupt ATP production through several mechanisms. At the level of the citric acid cycle, arsenic inhibits pyruvate dehydrogenase and by co...more Number of Targets: 44 |
| T3D4330 | Glyceric acid 473-81-4 | C3H6O4 106.077 g/mol |  |
| Glyceric acid is a compound that is secreted excessively in the urine by patients suffering from D-glyceric aciduria and D-glycerate anemia. Deficiency of human glycer...more Number of Targets: 1 |
| T3D0058 | m-Xylene 108-38-3 | C8H10 106.165 g/mol |  |
| m-Xylene is a cholinesterase or acetylcholinesterase (AChE) inhibitor. A cholinesterase inhibitor (or 'anticholinesterase') suppresses the action of acetylcholinestera...more Number of Targets: 5 |
| T3D0099 | Ethylbenzene 100-41-4 | C8H10 106.165 g/mol |  |
| Changes in the integrity of the cell membrane after partitioning of ethylbenzene into the lipid bilayer may subsequently affect the function of membrane, particularly ...more Number of Targets: 17 |
| T3D0185 | p-Xylene 106-42-3 | C8H10 106.165 g/mol |  |
| p-Xylene is a cholinesterase or acetylcholinesterase (AChE) inhibitor. A cholinesterase inhibitor (or 'anticholinesterase') suppresses the action of acetylcholinestera...more Number of Targets: 4 |
| T3D0864 | o-Xylene 95-47-6 | C8H10 106.165 g/mol |  |
| o-Xylene is a cholinesterase or acetylcholinesterase (AChE) inhibitor. A cholinesterase inhibitor (or 'anticholinesterase') suppresses the action of acetylcholinestera...more Number of Targets: 4 |
| T3D1916 | Lithium perchlorate 7791-03-9 | ClLiO4 106.392 g/mol |  |
| The primary and most sensitive target of the perchlorate anion (perchlorate) is the thyroid gland. Perchlorate inhibits the transport of iodide (I-) from the blood int...more Number of Targets: 2 |
| T3D0180 | Palladium 7440-05-03 | Pd 106.420 g/mol |  |
| Palladium ions are able to inhibit most major cellular fuctions. They form strong complexes with both inorganic and organic ligands, substitute essential ions, bind to...more Number of Targets: 5 |
| T3D1806 | Vinyl bromide 593-60-2 | C2H3Br 106.949 g/mol |  |
| Organobromide compounds, especially alkylbromides are strong alkylating agents. Consequently they can randomly modify the surfaces of proteins and lipids, leading to ...more Number of Targets: 2 |
| T3D4217 | O-Toluidine 95-53-4 | C7H9N 107.153 g/mol |  |
| Not Available Number of Targets: 1 |
| T3D0214 | Silver 7440-22-4 | Ag 107.868 g/mol |  |
| Metallic silver is oxidized and may deposit in the tissues, causing arygria. The silver ion is known to inhibit glutathione peroxidase and NA+,K+-ATPase activity, resp...more Number of Targets: 18 |
| T3D1632 | Vanadium(III) fluoride 10049-12-4 | F3V 107.937 g/mol |  |
| Vanadium damages alveolar macrophages by decreasing the macrophage membrane integrity, thus impairing the cells' phagocytotic ability and viability. The pentavalent fo...more Number of Targets: 47 |
| T3D0277 | Arsenic disulfide 1303-32-8 | AsHS 107.995 g/mol |  |
| Arsenic and its metabolites disrupt ATP production through several mechanisms. At the level of the citric acid cycle, arsenic inhibits pyruvate dehydrogenase and by co...more Number of Targets: 44 |
| T3D1508 | Aluminium(II) oxide 457-64-8 | Al2H6O3 108.009 g/mol |  |
| The main target organs of aluminum are the central nervous system and bone. Aluminum binds with dietary phosphorus and impairs gastrointestinal absorption of phosphoru...more Number of Targets: 3 |
| T3D4578 | Quinone 106-51-4 | C6H4O2 108.095 g/mol |  |
| Quinone is a cholinesterase or acetylcholinesterase (AChE) inhibitor. A cholinesterase inhibitor (or 'anticholinesterase') suppresses the action of acetylcholinesteras...more Number of Targets: 9 |
| T3D0170 | p-Cresol 106-44-5 | C7H8O 108.138 g/mol |  |
| p-Cresol is a cholinesterase or acetylcholinesterase (AChE) inhibitor. A cholinesterase inhibitor (or 'anticholinesterase') suppresses the action of acetylcholinestera...more Number of Targets: 5 |
| T3D0196 | o-Cresol 95-48-7 | C7H8O 108.138 g/mol |  |
| Target organs of ingested cresols in humans are the blood, kidneys, lungs, liver, heart, and central nervous system. Cresols impair the stratum corneum and produce coa...more Number of Targets: 3 |