Browsing Toxins By Category
Displaying toxin 526 - 550 of 3678 in total
| T3DB ID | Name CAS Number | Formula Weight | Structure | Type | Mechanism of Toxicity |
|---|---|---|---|---|---|
| T3D4818 | Bicalutamide 90357-06-5 | C18H14F4N2O4S 430.373 g/mol |  |
| Bicalutamide competes with androgen for the binding of androgen receptors, consequently blocking the action of androgens of adrenal and testicular origin which stimula...more Number of Targets: 5 |
| T3D1884 | Tetrabutylantimony(V) bromide 45212-19-9 | C16H36BrSb 430.120 g/mol |  |
| The inhalation data suggests that the myocardium is a target of antimony toxicity. It is possible that antimony affects circulating glucose by interfering with enzymes...more Number of Targets: 20 |
| T3D1303 | p-Azobenzenearsonate 7334-23-8 | C12H12As2N2O6 430.077 g/mol |  |
| Arsenic and its metabolites disrupt ATP production through several mechanisms. At the level of the citric acid cycle, arsenic inhibits pyruvate dehydrogenase and by co...more Number of Targets: 44 |
| T3D0594 | 2,3,3',4,4',5,5',6-Octachlorobiphenyl 74472-53-0 | C12H2Cl8 429.768 g/mol |  |
| The mechanism of action varies with the specific PCB. Dioxin-like PCBs bind to the aryl hydrocarbon receptor, which disrupts cell function by altering the transcriptio...more Number of Targets: 7 |
| T3D0593 | 2,2',3,4,4',5,6,6'-Octachlorobiphenyl 74472-52-9 | C12H2Cl8 429.768 g/mol |  |
| The mechanism of action varies with the specific PCB. Dioxin-like PCBs bind to the aryl hydrocarbon receptor, which disrupts cell function by altering the transcriptio...more Number of Targets: 7 |
| T3D0592 | 2,2',3,4,4',5,5',6-Octachlorobiphenyl 52663-76-0 | C12H2Cl8 429.768 g/mol |  |
| The mechanism of action varies with the specific PCB. Dioxin-like PCBs bind to the aryl hydrocarbon receptor, which disrupts cell function by altering the transcriptio...more Number of Targets: 7 |
| T3D0591 | 2,2',3,3',5,5',6,6'-Octachlorobiphenyl 2136-99-4 | C12H2Cl8 429.768 g/mol |  |
| The mechanism of action varies with the specific PCB. Dioxin-like PCBs bind to the aryl hydrocarbon receptor, which disrupts cell function by altering the transcriptio...more Number of Targets: 7 |
| T3D0590 | 2,2',3,3',4,5',6,6'-Octachlorobiphenyl 40186-71-8 | C12H2Cl8 429.768 g/mol |  |
| The mechanism of action varies with the specific PCB. Dioxin-like PCBs bind to the aryl hydrocarbon receptor, which disrupts cell function by altering the transcriptio...more Number of Targets: 7 |
| T3D0589 | 2,2',3,3',4,5,6,6'-Octachlorobiphenyl 52663-73-7 | C12H2Cl8 429.768 g/mol |  |
| The mechanism of action varies with the specific PCB. Dioxin-like PCBs bind to the aryl hydrocarbon receptor, which disrupts cell function by altering the transcriptio...more Number of Targets: 7 |
| T3D0588 | 2,2',3,3',4,5,5',6'-Octachlorobiphenyl 52663-75-9 | C12H2Cl8 429.768 g/mol |  |
| The mechanism of action varies with the specific PCB. Dioxin-like PCBs bind to the aryl hydrocarbon receptor, which disrupts cell function by altering the transcriptio...more Number of Targets: 7 |
| T3D0587 | 2,2',3,3',4,5,5',6-Octachlorobiphenyl 68194-17-2 | C12H2Cl8 429.768 g/mol |  |
| The mechanism of action varies with the specific PCB. Dioxin-like PCBs bind to the aryl hydrocarbon receptor, which disrupts cell function by altering the transcriptio...more Number of Targets: 7 |
| T3D0586 | 2,2',3,3',4,4',6,6'-Octachlorobiphenyl 33091-17-7 | C12H2Cl8 429.768 g/mol |  |
| The mechanism of action varies with the specific PCB. Dioxin-like PCBs bind to the aryl hydrocarbon receptor, which disrupts cell function by altering the transcriptio...more Number of Targets: 7 |
| T3D0585 | 2,2',3,3',4,4',5,6'-Octachlorobiphenyl 42740-50-1 | C12H2Cl8 429.768 g/mol |  |
| The mechanism of action varies with the specific PCB. Dioxin-like PCBs bind to the aryl hydrocarbon receptor, which disrupts cell function by altering the transcriptio...more Number of Targets: 7 |
| T3D0584 | 2,2',3,3',4,4',5,6-Octachlorobiphenyl 52663-78-2 | C12H2Cl8 429.768 g/mol |  |
| The mechanism of action varies with the specific PCB. Dioxin-like PCBs bind to the aryl hydrocarbon receptor, which disrupts cell function by altering the transcriptio...more Number of Targets: 7 |
| T3D0583 | 2,2',3,3',4,4',5,5'-Octachlorobiphenyl 35694-08-7 | C12H2Cl8 429.768 g/mol |  |
| The mechanism of action varies with the specific PCB. Dioxin-like PCBs bind to the aryl hydrocarbon receptor, which disrupts cell function by altering the transcriptio...more Number of Targets: 7 |
| T3D2907 | Mifepristone 84371-65-3 | C29H35NO2 429.594 g/mol |  |
| Mifepristone is a cholinesterase or acetylcholinesterase (AChE) inhibitor. A cholinesterase inhibitor (or 'anticholinesterase') suppresses the action of acetylcholines...more Number of Targets: 23 |
| T3D2722 | Oxiconazole 64211-46-7 | C18H13Cl4N3O 429.127 g/mol |  |
| Oxiconazole inhibits ergosterol biosynthesis, which is required for cytoplasmic membrane integrity of fungi. It acts to destabilize the fungal cyctochrome P450 51 enzy...more Number of Targets: 1 |
| T3D4792 | 17-Hydroxyprogesterone caproate 630-56-8 | C27H40O4 428.604 g/mol |  |
| Not Available Number of Targets: 7 |
| T3D4854 | Sorbitan oleate 1338-43-8 | C24H44O6 428.603 g/mol |  |
| Not Available Number of Targets: 2 |
| T3D3499 | Darifenacin 133099-04-4 | C28H30N2O2 426.550 g/mol |  |
| Darifenacin selectively antagonizes the muscarinic M3 receptor. M3 receptors are involved in contraction of human bladder and gastrointestinal smooth muscle, saliva pr...more Number of Targets: 5 |
| T3D4083 | Jervine 469-59-0 | C27H39NO3 425.604 g/mol |  |
| Jervine's biological activity is mediated via its interaction with the 7 pass trans membrane protein smoothened. Jervine binds with and inhibits smoothened, which is a...more Number of Targets: 3 |
| T3D4954 | 2,3,4,6,7,8,11-Heptachlorotridecane Not Available | C13H21Cl7 425.477 g/mol |  |
| Not Available Number of Targets: 1 |
| T3D2117 | 1,2,3,4,6,7,9-Heptachlorodibenzo-p-dioxin 58200-70-7 | C12HCl7O2 425.306 g/mol |  |
| CDDs cause their toxic effects by binding to the aryl hydrocarbon receptor and subsequently altering the transcription of certain genes. The affinity for the Ah recept...more Number of Targets: 3 |
| T3D2116 | 1,2,3,4,6,7,8-Heptachlorodibenzo-p-dioxin 35822-46-9 | C12HCl7O2 425.306 g/mol |  |
| CDDs cause their toxic effects by binding to the aryl hydrocarbon receptor and subsequently altering the transcription of certain genes. The affinity for the Ah recept...more Number of Targets: 3 |
| T3D3497 | Clindamycin 18323-44-9 | C18H33ClN2O5S 424.983 g/mol |  |
| Systemic/vaginal clindamycin inhibits protein synthesis of bacteria by binding to the 50S ribosomal subunits of the bacteria. Specifically, it binds primarily to the 2...more Number of Targets: 0 |