Browsing Toxins By Category
| T3DB ID | Name CAS Number | Formula Weight | Structure | Type | Mechanism of Toxicity |
|---|---|---|---|---|---|
| T3D2055 | 1,9-Dichlorodibenzo-p-dioxin 64560-13-0 | C12H6Cl2O2 253.081 g/mol |  |
| CDDs cause their toxic effects by binding to the aryl hydrocarbon receptor and subsequently altering the trascription of certain genes. The affinity for the Ah recepto...more Number of Targets: 4 |
| T3D2419 | 1,9-Dichlorodibenzofuran 70648-14-5 | C12H6Cl2O 237.081 g/mol |  |
| Halogenated dibenzofurans (PCDFs and PBDFs) bind the aryl hydrocarbon receptor (AhR), which increases its ability to activate transcription in the XRE (xenobiotic reso...more Number of Targets: 2 |
| T3D1065 | 1-(4,5-Dihydro-1H-imidazol-2-ylmethyl)-2,3,4,5-tetrahydro-1-benzazepine 24483-78-1 | C14H19N3 229.321 g/mol |  |
| Acts as a neurotransmitter mimic , having both excitatory and depressant effects, eventually blocking postsynaptic nicotinic receptors. (T10) Number of Targets: 5 |
| T3D1069 | 1-(Cyclopropylmethyl)-2-(nitromethylidene)pyrrolidine 60737-54-4 | C9H14N2O2 182.220 g/mol |  |
| Acts as a neurotransmitter mimic , having both excitatory and depressant effects, eventually blocking postsynaptic nicotinic receptors. (T10) Number of Targets: 5 |
| T3D1775 | 1-Bromo-3-chloro-5,5-dimethylhydantoin 16079-88-2 | C5H6BrClN2O2 241.470 g/mol |  |
| BCDMH likely causes tissue irritation through its breakdown products (hypochlorous acid and hypobromous acid) which, on their own, can cause local irritation. 5,5-dim...more Number of Targets: 3 |
| T3D1781 | 1-Bromobutane 109-65-9 | C4H9Br 137.018 g/mol |  |
| 1-bromobutane reacts quickly with hepatic glutathione (GSH) leading to its rapid depletion. This can cause liver damage and has been shown to increase serum levels of...more Number of Targets: 3 |
| T3D1786 | 1-Bromohexane 111-25-1 | C6H13Br 165.071 g/mol |  |
| Bromine is a powerful oxidizing agent and is able to release oxygen free radicals from the water in mucous membranes. These free radicals are also potent oxidizers and...more Number of Targets: 0 |
| T3D1802 | 1-Bromopropane 106-94-5 | C3H7Br 122.992 g/mol |  |
| Organobromide compounds, especially alkylbromides are strong alkylating agents. Consequently they can randomly modify the surfaces of proteins and lipids, leading to ...more Number of Targets: 4 |
| T3D2046 | 1-Chlorodibenzo-p-dioxin 39227-53-7 | C12H7ClO2 218.636 g/mol |  |
| CDDs cause their toxic effects by binding to the aryl hydrocarbon receptor and subsequently altering the trascription of certain genes. The affinity for the Ah recepto...more Number of Targets: 4 |
| T3D2215 | 1-Chlorodibenzofuran 42934-53-2 | C12H7ClO 202.636 g/mol |  |
| Halogenated dibenzofurans (PCDFs and PBDFs) bind the aryl hydrocarbon receptor (AhR), which increases its ability to activate transcription in the XRE (xenobiotic reso...more Number of Targets: 2 |
| T3D4863 | 1-Hexadecanol 36653-82-4 | C16H34O 242.441 g/mol |  |
| Not Available Number of Targets: 2 |
| T3D4900 | 1-Hexanol 111-27-3 | C6H14O 102.175 g/mol |  |
| Not Available Number of Targets: 1 |
| T3D3971 | 1-Hydroxypyrene 5315-79-7 | C16H12O 220.266 g/mol |  |
| Not Available Number of Targets: 15 |
| T3D4946 | 1-Methyl-2-pyrrolidone 872-50-4 | C5H9NO 99.131 g/mol |  |
| Not Available Number of Targets: 1 |
| T3D3474 | 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine 28289-54-5 | C12H15N 173.254 g/mol |  |
| MPTP itself is not toxic, and as a lipophilic compound can cross the blood-brain barrier. Once inside the brain, MPTP is metabolized into the toxic cation 1-methyl-4-p...more Number of Targets: 1 |
| T3D4581 | 1-Methyl-6-phenyl-1H-imidazo[4,5-b]pyridin-2-amine 105650-23-5 | C13H12N4 224.261 g/mol |  |
| Not Available Number of Targets: 1 |
| T3D0628 | 1-Methylnaphthalene 90-12-0 | C11H10 142.197 g/mol |  |
| The ability of PAH's to bind to blood proteins such as albumin allows them to be transported throughout the body. Many PAH's induce the expression of cytochrome P450 e...more Number of Targets: 5 |
| T3D3968 | 1-Naphthol 90-15-3 | C10H8O 144.170 g/mol |  |
| 1-Naphthol is a cholinesterase or acetylcholinesterase (AChE) inhibitor. A cholinesterase inhibitor (or 'anticholinesterase') suppresses the action of acetylcholineste...more Number of Targets: 5 |
| T3D4944 | 1-Nitronaphthalene 86-57-7 | C10H7NO2 173.168 g/mol |  |
| 1-Nitronaphthalene and its reactive products specifically targets the airway epithelium. Its toxicity is synergized by prior long-term ozone exposure. 1-NN appears to ...more Number of Targets: 4 |
| T3D4829 | 1-Octen-3-Ol 3391-86-4 | C8H16O 128.212 g/mol |  |
| Not Available Number of Targets: 1 |
| T3D3458 | 1-Pentene 109-67-1 | C5H10 70.133 g/mol |  |
| Petroleum distillates are central nervous system depressants and cause pulmonary damage. During metabolism. 1-pentene is oxidized at the double bond and excreted as th...more Number of Targets: 0 |
| T3D4965 | 1-Pyrroline-5-carboxylic acid 2906-39-0 | C5H7NO2 113.115 g/mol |  |
| Not Available Number of Targets: 0 |
| T3D1084 | 1-[(6-Chloropyridin-3-yl)methyl]-2-(nitromethylidene)-1,3-diazinane 72126-78-4 | C11H13ClN4O2 268.700 g/mol |  |
| Acts as a neurotransmitter mimic , having both excitatory and depressant effects, eventually blocking postsynaptic nicotinic receptors. (T10) Number of Targets: 7 |
| T3D3701 | 15-Acetyl-4-deoxynivalenol 88337-96-6 | C17H22O7 338.352 g/mol |  |
| Unlike many other mycotoxins, trichothecenes do not require metabolic activation to exert their biological activity, instead directly reacting with cellular components...more Number of Targets: 2 |
| T3D3703 | 15-Deacetylcalonectrin 38818-66-5 | C17H24O5 308.370 g/mol |  |
| Unlike many other mycotoxins, trichothecenes do not require metabolic activation to exert their biological activity, instead directly reacting with cellular components...more Number of Targets: 2 |