Browsing Toxins By Category
| T3DB ID | Name CAS Number | Formula Weight | Structure | Type | Mechanism of Toxicity |
|---|---|---|---|---|---|
| T3D2699 | Vitamin A 68-26-8 | C20H30O 286.452 g/mol |  |
| Vision:Vitamin A (all-trans retinol) is converted in the retina to the 11-cis-isomer of retinaldehyde or 11-cis-retinal. 11-cis-retinal functions in the retina in the ...more Number of Targets: 32 |
| T3D2643 | Vipoxin Not Available | Not Available 13827.665 g/mol |  |
| Vipoxin inhibits the binding of ligands to biogenic amine receptors including dopamine,
serotonin and alpha1/alpha2 adrenergic receptors. Vipoxin also exhibits hemoly...more Number of Targets: 28 |
| T3D2642 | Viperotoxin Not Available | Not Available 15554.775 g/mol |  |
| Viperotoxin is a presynaptic neurotoxin. (T170) Number of Targets: 0 |
| T3D0004 | Vinyl chloride 75-01-4 | C2H3Cl 62.498 g/mol |  |
| Vinyl chloride poisoning exhibits many of the characteristics of autoimmune diseases. This is believed to be the result of a reactive vinyl chloride intermediate metab...more Number of Targets: 43 |
| T3D1806 | Vinyl bromide 593-60-2 | C2H3Br 106.949 g/mol |  |
| Organobromide compounds, especially alkylbromides are strong alkylating agents. Consequently they can randomly modify the surfaces of proteins and lipids, leading to ...more Number of Targets: 2 |
| T3D2479 | Vindesine 53643-48-4 | C43H55N5O7 753.926 g/mol |  |
| Vindesine acts by causing the arrest of cells in metaphase mitosis through its inhibition tubulin mitotic funcitoning. The drug is cell-cycle specific for the S phase. Number of Targets: 1 |
| T3D4016 | Vincristine 57-22-7 | C46H56N4O10 824.958 g/mol |  |
| The antitumor activity of Vincristine is thought to be due primarily to inhibition of mitosis at metaphase through its interaction with tubulin. Like other vinca alkal...more Number of Targets: 7 |
| T3D3942 | Vinclozolin 50471-44-8 | C12H9Cl2NO3 286.111 g/mol |  |
| Vinclozolin and some of its metabolites have antiandrogenic activity. Vinclozolin's main toxic effects are related to its antiandrogenic activity. They compete with an...more Number of Targets: 11 |
| T3D4017 | Vinblastine 865-21-4 | C46H58N4O9 810.974 g/mol |  |
| The antitumor activity of vinblastine is thought to be due primarily to inhibition of mitosis at metaphase through its interaction with tubulin. Vinblastine binds to t...more Number of Targets: 6 |
| T3D2977 | Vigabatrin 60643-86-9 | C6H11NO2 129.157 g/mol |  |
| Vigabatrin increases brain concentrations of gamma-aminobutyric acid (GABA), an inhibitory neurotransmitter in the CNS, by irreversibly inhibiting enzymes that catabol...more Number of Targets: 2 |
| T3D2496 | Versutoxin 114264-83-4 | Not Available 4855.645 g/mol |  |
| Versutoxin inhibits both insect and mammalian voltage-gated sodium channels. It binds to site 3 in tetrodotoxin-sensitive sodium channels, which slows their inactivati...more Number of Targets: 14 |
| T3D3782 | Verruculogen 12771-72-1 | C27H33N3O7 511.567 g/mol |  |
| Tremorgenic mycotoxins exert their toxic effects by interfering with neurotransmitter release, possibly by causing degeneration of nerve terminals. They are thought to...more Number of Targets: 28 |
| T3D3781 | Verrucosidin 88389-71-3 | C24H32O6 416.507 g/mol |  |
| Tremorgenic mycotoxins exert their toxic effects by interfering with neurotransmitter release, possibly by causing degeneration of nerve terminals. They are thought to...more Number of Targets: 23 |
| T3D3723 | Verrucarol 2198-92-7 | C15H22O4 266.333 g/mol |  |
| Unlike many other mycotoxins, trichothecenes do not require metabolic activation to exert their biological activity, instead directly reacting with cellular components...more Number of Targets: 2 |
| T3D3722 | Verrucarin J 4643-58-7 | C27H32O8 484.538 g/mol |  |
| Unlike many other mycotoxins, trichothecenes do not require metabolic activation to exert their biological activity, instead directly reacting with cellular components...more Number of Targets: 2 |
| T3D3721 | Verrucarin B 2290-11-1 | C27H32O9 500.538 g/mol |  |
| Unlike many other mycotoxins, trichothecenes do not require metabolic activation to exert their biological activity, instead directly reacting with cellular components...more Number of Targets: 2 |
| T3D3720 | Verrucarin A 3148-09-2 | C27H34O9 502.554 g/mol |  |
| Unlike many other mycotoxins, trichothecenes do not require metabolic activation to exert their biological activity, instead directly reacting with cellular components...more Number of Targets: 2 |
| T3D1020 | Vernolate 1929-77-7 | C10H21NOS 203.345 g/mol |  |
| Some thiocarbamates (EPTC, Molinate, Pebulate, and Cycloate) share a common mechanism of toxicity, i.e. the inhibition of acetylcholinesterase. An acetylcholinesterase...more Number of Targets: 4 |
| T3D4061 | Veratridine 71-62-5 | C36H51NO11 673.790 g/mol |  |
| Veratridine is a steroid-derived alkaloid from plants in the Liliaceae family that functions as a neurotoxin by abolishing inactivation of sodium ion channels. It bind...more Number of Targets: 0 |
| T3D4084 | Veratramine 60-70-8 | C27H39NO2 409.604 g/mol |  |
| Veratramine produces a characteristic excitatory action on the central nervous system, producing both tremor and a characteristic "struggling" behavior. This behaviora...more Number of Targets: 0 |
| T3D3544 | Verapamil 52-53-9 | C27H38N2O4 454.602 g/mol |  |
| Verapamil inhibits voltage-dependent calcium channels. Specifically, its effect on L-type calcium channels in the heart causes a reduction in ionotropy and chronotropy...more Number of Targets: 21 |
| T3D2736 | Venlafaxine 93413-69-5 | C17H27NO2 277.402 g/mol |  |
| The exact mechanism of action of venlafaxine is unknown, but appears to be associated with the its potentiation of neurotrasmitter activity in the CNS. Venlafaxine and...more Number of Targets: 19 |
| T3D2577 | Varenicline 249296-44-4 | C13H13N3 211.262 g/mol |  |
| Varenicline is an alpha-4 beta-2 neuronal nicotinic acetylcholine receptor partial agonist. The drug shows high selectiviyty for this receptor subclass, relative to ot...more Number of Targets: 4 |
| T3D3067 | Vapreotide 103222-11-3 | C57H70N12O9S2 1131.371 g/mol |  |
| The exact mechanism of action is unknown, although one study has provided in vitro and in vivo evidence for a tachykinin NK1 receptor antagonist effect in the analgesi...more Number of Targets: 3 |
| T3D4849 | Vanillin 121-33-5 | C8H8O3 152.147 g/mol |  |
| Not Available Number of Targets: 1 |