Browsing Toxins By Category
Displaying toxin 3626 - 3650 of 3678 in total
| T3DB ID | Name CAS Number | Formula Weight | Structure | Type | Mechanism of Toxicity |
|---|---|---|---|---|---|
| T3D2141 | 1,2,3,4,6,9-Hexachlorodibenzofuran 91538-83-9 | C12H2Cl6O 374.862 g/mol |  |
| Halogenated dibenzofurans (PCDFs and PBDFs) bind the aryl hydrocarbon receptor (AhR), which increases its ability to activate transcription in the XRE (xenobiotic reso...more Number of Targets: 2 |
| T3D2113 | 1,2,3,4,6,9-Hexachlorodibenzo-p-dioxin 58200-68-3 | C12H2Cl6O2 390.861 g/mol |  |
| CDDs cause their toxic effects by binding to the aryl hydrocarbon receptor and subsequently altering the transcription of certain genes. The affinity for the Ah recept...more Number of Targets: 3 |
| T3D2140 | 1,2,3,4,6,8-Hexachlorodibenzofuran 69698-60-8 | C12H2Cl6O 374.862 g/mol |  |
| Halogenated dibenzofurans (PCDFs and PBDFs) bind the aryl hydrocarbon receptor (AhR), which increases its ability to activate transcription in the XRE (xenobiotic reso...more Number of Targets: 2 |
| T3D2115 | 1,2,3,4,6,8-Hexachlorodibenzo-p-dioxin 58200-67-2 | C12H2Cl6O2 390.861 g/mol |  |
| CDDs cause their toxic effects by binding to the aryl hydrocarbon receptor and subsequently altering the transcription of certain genes. The affinity for the Ah recept...more Number of Targets: 3 |
| T3D2139 | 1,2,3,4,6,8,9-Heptachlorodibenzofuran 69698-58-4 | C12HCl7O 409.307 g/mol |  |
| Halogenated dibenzofurans (PCDFs and PBDFs) bind the aryl hydrocarbon receptor (AhR), which increases its ability to activate transcription in the XRE (xenobiotic reso...more Number of Targets: 2 |
| T3D2138 | 1,2,3,4,6,7-Hexachlorodibenzofuran 79060-60-9 | C12H2Cl6O 374.862 g/mol |  |
| Halogenated dibenzofurans (PCDFs and PBDFs) bind the aryl hydrocarbon receptor (AhR), which increases its ability to activate transcription in the XRE (xenobiotic reso...more Number of Targets: 2 |
| T3D2110 | 1,2,3,4,6,7-Hexachlorodibenzo-p-dioxin 58200-66-1 | C12H2Cl6O2 390.861 g/mol |  |
| CDDs cause their toxic effects by binding to the aryl hydrocarbon receptor and subsequently altering the transcription of certain genes. The affinity for the Ah recept...more Number of Targets: 3 |
| T3D2137 | 1,2,3,4,6,7-Hexabromodibenzofuran 124388-78-9 | C12H2Br6O 641.568 g/mol |  |
| Halogenated dibenzofurans (PCDFs and PBDFs) bind the aryl hydrocarbon receptor (AhR), which increases its ability to activate transcription in the XRE (xenobiotic reso...more Number of Targets: 2 |
| T3D2358 | 1,2,3,4,6,7-Hexabromo-8,9-dichlorodibenzofuran 107207-36-3 | C12Br6Cl2O 710.458 g/mol |  |
| Halogenated dibenzofurans (PCDFs and PBDFs) bind the aryl hydrocarbon receptor (AhR), which increases its ability to activate transcription in the XRE (xenobiotic reso...more Number of Targets: 2 |
| T3D2136 | 1,2,3,4,6,7,9-Heptachlorodibenzofuran 70648-25-8 | C12HCl7O 409.307 g/mol |  |
| Halogenated dibenzofurans (PCDFs and PBDFs) bind the aryl hydrocarbon receptor (AhR), which increases its ability to activate transcription in the XRE (xenobiotic reso...more Number of Targets: 2 |
| T3D2117 | 1,2,3,4,6,7,9-Heptachlorodibenzo-p-dioxin 58200-70-7 | C12HCl7O2 425.306 g/mol |  |
| CDDs cause their toxic effects by binding to the aryl hydrocarbon receptor and subsequently altering the transcription of certain genes. The affinity for the Ah recept...more Number of Targets: 3 |
| T3D0166 | 1,2,3,4,6,7,8-Heptachlorodibenzofuran 38998-75-3 | C12HCl7O 409.307 g/mol |  |
| Halogenated dibenzofurans (PCDFs and PBDFs) bind the aryl hydrocarbon receptor (AhR), which increases its ability to activate transcription in the XRE (xenobiotic reso...more Number of Targets: 2 |
| T3D2116 | 1,2,3,4,6,7,8-Heptachlorodibenzo-p-dioxin 35822-46-9 | C12HCl7O2 425.306 g/mol |  |
| CDDs cause their toxic effects by binding to the aryl hydrocarbon receptor and subsequently altering the transcription of certain genes. The affinity for the Ah recept...more Number of Targets: 3 |
| T3D2134 | 1,2,3,4,6,7,8-Heptabromodibenzofuran 107555-95-3 | C12HBr7O 720.464 g/mol |  |
| Halogenated dibenzofurans (PCDFs and PBDFs) bind the aryl hydrocarbon receptor (AhR), which increases its ability to activate transcription in the XRE (xenobiotic reso...more Number of Targets: 2 |
| T3D0162 | 1,2,3,4,6,7,8,9-Octachlorodibenzofuran 39001-02-0 | C12Cl8O 443.752 g/mol |  |
| Halogenated dibenzofurans (PCDFs and PBDFs) bind the aryl hydrocarbon receptor (AhR), which increases its ability to activate transcription in the XRE (xenobiotic reso...more Number of Targets: 2 |
| T3D2132 | 1,2,3,4,6,7,8,9,10,10,11,11-Dodecachloro-1,4,4a,5a,6,9,9a,9b-octahydro-1,4:6,9- dimethanodibenzofuran 31107-44-5 | C14H5Cl11O 579.172 g/mol |  |
| Halogenated dibenzofurans (PCDFs and PBDFs) bind the aryl hydrocarbon receptor (AhR), which increases its ability to activate transcription in the XRE (xenobiotic reso...more Number of Targets: 2 |
| T3D4815 | 1,10-Phenanthroline 66-71-7 | C12H8N2 180.205 g/mol |  |
| Not Available Number of Targets: 6 |
| T3D3522 | 1,1-Dimethylbiguanide 657-24-9 | C4H11N5 129.164 g/mol |  |
| Metformin's mechanisms of action differ from other classes of oral antihyperglycemic agents. Metformin decreases blood glucose levels by decreasing hepatic glucose pro...more Number of Targets: 4 |
| T3D1908 | 1,1-Dichloropropene 563-58-6 | C3H4Cl2 110.970 g/mol |  |
| The primary toxic effects of 1,1-dichloropropene are portal-of-entry effects resulting from the chemical reactivity of the compound and its physicochemical properties....more Number of Targets: 3 |
| T3D0079 | 1,1-Dichloroethene 75-35-4 | C2H2Cl2 96.943 g/mol |  |
| 1,1-Dichloroethene toxicity is caused by its reactive metabolites, which include epoxides, acyl chlorides, and halogenated aldehydes generated via oxidation by cytochr...more Number of Targets: 39 |
| T3D0160 | 1,1-Dichloroethane 75-34-3 | C2H4Cl2 98.959 g/mol |  |
| The limited information available about 1,1-dichloroethane suggests that it may be nephrotoxic, fetotoxic, and possibly carcinogenic. 1,1-Dichloroethane has been obser...more Number of Targets: 40 |
| T3D1793 | 1,1-Dibromoethane 557-91-5 | C2H4Br2 187.861 g/mol |  |
| Bromine is a powerful oxidizing agent and is able to release oxygen free radicals from the water in mucous membranes. These free radicals are also potent oxidizers and...more Number of Targets: 0 |
| T3D0163 | 1,1,2-Trichloroethane 79-00-5 | C2H3Cl3 133.404 g/mol |  |
| Acyl chlorides and free radicals formed during the metabolism of 1,1,2-trichloroethane are reactive metabolites that can bind to proteins and nucleic acids (DNA, RNA),...more Number of Targets: 5 |
| T3D0146 | 1,1,2,2-Tetrachloroethane 79-34-5 | C2H2Cl4 167.849 g/mol |  |
| The presence of the functional group consisting of a terminal dichloromethyl moiety in a molecule is known to confer toxicity. Moreover, the metabolism of 1,1,2,2-tetr...more Number of Targets: 39 |
| T3D1804 | 1,1,2,2-Tetrabromoethane 79-27-6 | C2H2Br4 345.653 g/mol |  |
| Bromine is a powerful oxidizing agent and is able to release oxygen free radicals from the water in mucous membranes. These free radicals are also potent oxidizers and...more Number of Targets: 0 |