NADH dehydrogenase [ubiquinone] iron-sulfur protein 5

NameNADH dehydrogenase [ubiquinone] iron-sulfur protein 5
Synonyms
  • CI-15 kDa
  • Complex I-15 kDa
  • NADH-ubiquinone oxidoreductase 15 kDa subunit
Gene NameNDUFS5
OrganismHuman
Amino acid sequence
>lcl|BSEQ0009927|NADH dehydrogenase [ubiquinone] iron-sulfur protein 5
MPFLDIQKRFGLNIDRWLTIQSGEQPYKMAGRCHAFEKEWIECAHGIGYTRAEKECKIEY
DDFVECLLRQKTMRRAGTIRKQRDKLIKEGKYTPPPHHIGKGEPRP
Number of residues106
Molecular Weight12517.415
Theoretical pI9.54
GO Classification
Functions
  • NADH dehydrogenase (ubiquinone) activity
Processes
  • mitochondrial electron transport, NADH to ubiquinone
  • small molecule metabolic process
  • cellular metabolic process
  • mitochondrial respiratory chain complex I assembly
  • respiratory electron transport chain
Components
  • mitochondrion
  • mitochondrial inner membrane
  • mitochondrial respiratory chain complex I
  • mitochondrial intermembrane space
General FunctionNadh dehydrogenase (ubiquinone) activity
Specific FunctionAccessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
Pfam Domain Function
Transmembrane RegionsNot Available
GenBank Protein ID2911482
UniProtKB IDO43920
UniProtKB Entry NameNDUS5_HUMAN
Cellular LocationMitochondrion
Gene sequence
>lcl|BSEQ0009928|NADH dehydrogenase [ubiquinone] iron-sulfur protein 5 (NDUFS5)
ATGCCTTTCTTGGACATCCAGAAAAGGTTCGGCCTTAACATAGATCGATGGTTGACAATC
CAGAGTGGTGAACAGCCCTACAAGATGGCTGGTCGATGCCATGCTTTTGAAAAAGAATGG
ATAGAATGTGCACATGGAATCGGTTATACTCGGGCAGAGAAAGAGTGCAAGATAGAATAT
GATGATTTCGTAGAGTGTTTGCTTCGGCAGAAAACGATGAGACGTGCAGGTACCATCAGG
AAGCAGCGGGATAAGCTGATAAAGGAAGGAAAGTACACCCCTCCACCTCACCACATTGGC
AAGGGGGAGCCTCGGCCCTGA
GenBank Gene IDAF047434
GeneCard IDNot Available
GenAtlas IDNDUFS5
HGNC IDHGNC:7712
Chromosome Location1
Locus1p34.2-p33
References
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