- Effect
- Upregulated
- Gene
- NAD(P)H dehydrogenase, quinone 1
- Gene Symbol
- NQO1
- Gene ID
- 1728
- Interaction
- Thioctic Acid results in increased expression of NQO1 mRNA
- Chromosome
- 16q22.1
References
- Jia Z, Hallur S, Zhu H, Li Y, Misra HP: Potent upregulation of glutathione and NAD(P)H:quinone oxidoreductase 1 by alpha-lipoic acid in human neuroblastoma SH-SY5Y cells: protection against neurotoxicant-elicited cytotoxicity. Neurochem Res. 2008 May;33(5):790-800. Epub 2007 Oct 17. [17940886 ]
- Ade N, Leon F, Pallardy M, Peiffer JL, Kerdine-Romer S, Tissier MH, Bonnet PA, Fabre I, Ourlin JC: HMOX1 and NQO1 genes are upregulated in response to contact sensitizers in dendritic cells and THP-1 cell line: role of the Keap1/Nrf2 pathway. Toxicol Sci. 2009 Feb;107(2):451-60. doi: 10.1093/toxsci/kfn243. Epub 2008 Nov 25. [19033392 ]