- Effect
- Upregulated
- Gene
- cyclin-dependent kinase inhibitor 1A (p21, Cip1)
- Gene Symbol
- CDKN1A
- Gene ID
- 1026
- Interaction
- Cobalt results in increased expression of CDKN1A mRNA
- Chromosome
- 6p21.2
References
- Green SE, Luczak MW, Morse JL, DeLoughery Z, Zhitkovich A: Uptake, p53 pathway activation, and cytotoxic responses for Co(II) and Ni(II) in human lung cells: implications for carcinogenicity. Toxicol Sci. 2013 Dec;136(2):467-77. doi: 10.1093/toxsci/kft214. Epub 2013 Sep 25. [24068677 ]