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Displaying toxin 701 - 725 of 3678 in total
T3DB ID Name
CAS Number
Formula
Weight
StructureTypeMechanism of Toxicity
T3D4756Triamcinolone
124-94-7
C21H27FO6
394.434 g/mol
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  • Anti-Inflammatory Agent
  • Drug
  • Ester
  • Glucocorticoid
  • Metabolite
  • Organic Compound
  • Organofluoride
  • Synthetic Compound
The antiinflammatory actions of corticosteroids are thought to involve lipocortins, phospholipase A2 inhibitory proteins which, through inhibition of arachidonic acid,...more
Number of Targets: 5
T3D1181Uranyl nitrate
10102-06-4
N2O8U
394.038 g/mol
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  • Industrial/Workplace Toxin
  • Inorganic Compound
  • Nitrate
  • Nitrite
  • Pollutant
  • Radioactive
  • Synthetic Compound
  • Uranium Compound
Uranium is combined with either bicarbonate or a plasma protein in the blood but once in the kidney, it is released and forms complexes with phosphate ligands and prot...more
Number of Targets: 10
T3D4573Brotizolam
57801-81-7
C15H10BrClN4S
393.689 g/mol
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  • Bromide Compound
  • Drug
  • Organic Compound
  • Organobromide
  • Organochloride
  • Synthetic Compound
Benzodiazepines bind nonspecifically to benzodiazepine receptors BNZ1, which mediates sleep, and BNZ2, which affects affects muscle relaxation, anticonvulsant activity...more
Number of Targets: 19
T3D4674Amsacrine
51264-14-3
C21H19N3O3S
393.459 g/mol
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  • Amide
  • Antineoplastic Agent
  • Drug
  • Ether
  • Intercalating Agent
  • Metabolite
  • Organic Compound
  • Synthetic Compound
Amsacrine binds to DNA through intercalation and external binding. It has a base specificity for A-T pairs. Rapidly dividing cells are two to four times more sensitive...more
Number of Targets: 3
T3D1094Barium bromate
13967-90-3
BaBr2O6
393.131 g/mol
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  • Barium Compound
  • Bromate Compound
  • Industrial/Workplace Toxin
  • Inorganic Compound
  • Synthetic Compound
Barium is a competitive potassium channel antagonist that blocks the passive efflux of intracellular potassium, resulting in a shift of potassium from extracellular to...more
Number of Targets: 27
T3D4961Deoxycholic acid
83-44-3
C24H40O4
392.572 g/mol
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  • Animal Toxin
  • Metabolite
  • Natural Compound
Not Available
Number of Targets: 3
T3D4982Dexamethasone
50-02-2
C22H29FO5
392.461 g/mol
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  • Anti-Inflammatory Agent
  • Antiemetic
  • Antineoplastic Agent, Hormonal
  • Drug
  • Glucocorticoid
  • Metabolite
  • Synthetic Compound
Dexamethasone is a glucocorticoid agonist. Unbound dexamethasone crosses cell membranes and binds with high affinity to specific cytoplasmic glucocorticoid receptors. ...more
Number of Targets: 7
T3D1850Permethrin
52645-53-1
C21H20Cl2O3
391.288 g/mol
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  • Drug
  • Ester
  • Ether
  • Household Toxin
  • Metabolite
  • Organic Compound
  • Organochloride
  • Pesticide
  • Pyrethroid
  • Synthetic Compound
Pyrethroids exert their effect by prolonging the open phase of the sodium channel gates when a nerve cell is excited. They appear to bind to the membrane lipid phase i...more
Number of Targets: 26
T3D1112Barium iodide
13718-50-8
BaI2
391.136 g/mol
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  • Barium Compound
  • Industrial/Workplace Toxin
  • Inorganic Compound
  • Synthetic Compound
Barium is a competitive potassium channel antagonist that blocks the passive efflux of intracellular potassium, resulting in a shift of potassium from extracellular to...more
Number of Targets: 21
T3D2874Meclizine
569-65-3
C25H27ClN2
390.948 g/mol
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  • Amine
  • Anti-Allergic Agent
  • Antiemetic
  • Drug
  • Histamine Antagonist
  • Histamine H1 Antagonist
  • Metabolite
  • Organic Compound
  • Organochloride
  • Synthetic Compound
Along with its actions as an antagonist at H1-receptors, meclizine also possesses anticholinergic, central nervous system depressant, and local anesthetic effects. Mec...more
Number of Targets: 2
T3D19943,4',5-Tribromobiphenyl
72416-87-6
C12H7Br3
390.896 g/mol
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  • Aromatic Hydrocarbon
  • Bromide Compound
  • Industrial/Workplace Toxin
  • Organic Compound
  • Organobromide
  • Polybrominated Biphenyl
  • Synthetic Compound
The exact mechanism of toxicty of PBBs varies depending on the specific congener. The predominant interaction is believed to involve the aryl hydrocarbon receptor (AhR...more
Number of Targets: 1
T3D19823,4,4'-Tribromobiphenyl
6683-35-8
C12H7Br3
390.896 g/mol
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  • Aromatic Hydrocarbon
  • Bromide Compound
  • Industrial/Workplace Toxin
  • Organic Compound
  • Organobromide
  • Polybrominated Biphenyl
  • Synthetic Compound
The exact mechanism of toxicty of PBBs varies depending on the specific congener. The predominant interaction is believed to involve the aryl hydrocarbon receptor (AhR...more
Number of Targets: 1
T3D19802,4,4'-Tribromobiphenyl
6430-90-6
C12H7Br3
390.896 g/mol
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  • Aromatic Hydrocarbon
  • Bromide Compound
  • Industrial/Workplace Toxin
  • Organic Compound
  • Organobromide
  • Polybrominated Biphenyl
  • Synthetic Compound
The exact mechanism of toxicty of PBBs varies depending on the specific congener. The predominant interaction is believed to involve the aryl hydrocarbon receptor (AhR...more
Number of Targets: 1
T3D19792,4',6-Tribromobiphenyl
64258-03-3
C12H7Br3
390.896 g/mol
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  • Aromatic Hydrocarbon
  • Bromide Compound
  • Industrial/Workplace Toxin
  • Organic Compound
  • Organobromide
  • Polybrominated Biphenyl
  • Synthetic Compound
The exact mechanism of toxicty of PBBs varies depending on the specific congener. The predominant interaction is believed to involve the aryl hydrocarbon receptor (AhR...more
Number of Targets: 1
T3D19662,4',5-Tribromobiphenyl
59080-36-3
C12H7Br3
390.896 g/mol
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  • Aromatic Hydrocarbon
  • Bromide Compound
  • Industrial/Workplace Toxin
  • Organic Compound
  • Organobromide
  • Polybrominated Biphenyl
  • Synthetic Compound
The exact mechanism of toxicty of PBBs varies depending on the specific congener. The predominant interaction is believed to involve the aryl hydrocarbon receptor (AhR...more
Number of Targets: 1
T3D19652,3',5-Tribromobiphenyl
59080-35-2
C12H7Br3
390.896 g/mol
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  • Aromatic Hydrocarbon
  • Bromide Compound
  • Industrial/Workplace Toxin
  • Organic Compound
  • Organobromide
  • Polybrominated Biphenyl
  • Synthetic Compound
The exact mechanism of toxicty of PBBs varies depending on the specific congener. The predominant interaction is believed to involve the aryl hydrocarbon receptor (AhR...more
Number of Targets: 1
T3D19642,2',5-Tribromobiphenyl
59080-34-1
C12H7Br3
390.896 g/mol
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  • Aromatic Hydrocarbon
  • Bromide Compound
  • Industrial/Workplace Toxin
  • Organic Compound
  • Organobromide
  • Polybrominated Biphenyl
  • Synthetic Compound
The exact mechanism of toxicty of PBBs varies depending on the specific congener. The predominant interaction is believed to involve the aryl hydrocarbon receptor (AhR...more
Number of Targets: 1
T3D19632,4,6-Tribromobiphenyl
59080-33-0
C12H7Br3
390.896 g/mol
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  • Aromatic Hydrocarbon
  • Bromide Compound
  • Industrial/Workplace Toxin
  • Organic Compound
  • Organobromide
  • Polybrominated Biphenyl
  • Synthetic Compound
The exact mechanism of toxicty of PBBs varies depending on the specific congener. The predominant interaction is believed to involve the aryl hydrocarbon receptor (AhR...more
Number of Targets: 1
T3D1956Tribromobiphenyl
51202-79-0
C12H7Br3
390.896 g/mol
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  • Aromatic Hydrocarbon
  • Bromide Compound
  • Industrial/Workplace Toxin
  • Organic Compound
  • Organobromide
  • Polybrominated Biphenyl
  • Synthetic Compound
The exact mechanism of toxicty of PBBs varies depending on the specific congener. The predominant interaction is believed to involve the aryl hydrocarbon receptor (AhR...more
Number of Targets: 1
T3D19203,4,5-Tribromobiphenyl
115245-08-4
C12H7Br3
390.896 g/mol
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  • Aromatic Hydrocarbon
  • Bromide Compound
  • Industrial/Workplace Toxin
  • Organic Compound
  • Organobromide
  • Polybrominated Biphenyl
  • Synthetic Compound
The exact mechanism of toxicty of PBBs varies depending on the specific congener. The predominant interaction is believed to involve the aryl hydrocarbon receptor (AhR...more
Number of Targets: 1
T3D19192,4,5-Tribromobiphenyl
115245-07-3
C12H7Br3
390.896 g/mol
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  • Aromatic Hydrocarbon
  • Bromide Compound
  • Industrial/Workplace Toxin
  • Organic Compound
  • Organobromide
  • Polybrominated Biphenyl
  • Synthetic Compound
The exact mechanism of toxicty of PBBs varies depending on the specific congener. The predominant interaction is believed to involve the aryl hydrocarbon receptor (AhR...more
Number of Targets: 1
T3D21151,2,3,4,6,8-Hexachlorodibenzo-p-dioxin
58200-67-2
C12H2Cl6O2
390.861 g/mol
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  • Aromatic Hydrocarbon
  • Chlorinated Dibenzo-p-dioxin
  • Ether
  • Industrial By-product/Pollutant
  • Industrial/Workplace Toxin
  • Organic Compound
  • Organochloride
  • Pollutant
  • Synthetic Compound
CDDs cause their toxic effects by binding to the aryl hydrocarbon receptor and subsequently altering the transcription of certain genes. The affinity for the Ah recept...more
Number of Targets: 3
T3D21141,2,4,6,8,9-Hexachlorodibenzo-p-dioxin
58802-09-8
C12H2Cl6O2
390.861 g/mol
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  • Aromatic Hydrocarbon
  • Chlorinated Dibenzo-p-dioxin
  • Ether
  • Industrial By-product/Pollutant
  • Industrial/Workplace Toxin
  • Organic Compound
  • Organochloride
  • Pollutant
  • Synthetic Compound
CDDs cause their toxic effects by binding to the aryl hydrocarbon receptor and subsequently altering the trascription of certain genes. The affinity for the Ah recepto...more
Number of Targets: 4
T3D21131,2,3,4,6,9-Hexachlorodibenzo-p-dioxin
58200-68-3
C12H2Cl6O2
390.861 g/mol
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  • Aromatic Hydrocarbon
  • Chlorinated Dibenzo-p-dioxin
  • Ether
  • Industrial By-product/Pollutant
  • Industrial/Workplace Toxin
  • Organic Compound
  • Organochloride
  • Pollutant
  • Synthetic Compound
CDDs cause their toxic effects by binding to the aryl hydrocarbon receptor and subsequently altering the transcription of certain genes. The affinity for the Ah recept...more
Number of Targets: 3
T3D21121,2,3,6,8,9-Hexachlorodibenzo-p-dioxin
58200-69-4
C12H2Cl6O2
390.861 g/mol
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  • Aromatic Hydrocarbon
  • Chlorinated Dibenzo-p-dioxin
  • Ether
  • Industrial By-product/Pollutant
  • Industrial/Workplace Toxin
  • Organic Compound
  • Organochloride
  • Pollutant
  • Synthetic Compound
CDDs cause their toxic effects by binding to the aryl hydrocarbon receptor and subsequently altering the transcription of certain genes. The affinity for the Ah recept...more
Number of Targets: 3
Displaying toxin 701 - 725 of 3678 in total